Revolutionizing drug development: harnessing the potential of organ-on-chip technology for disease modeling and drug discovery

N Sunildutt, P Parihar… - Frontiers in …, 2023 - frontiersin.org
The inefficiency of existing animal models to precisely predict human pharmacological
effects is the root reason for drug development failure. Microphysiological system/organ-on …

[HTML][HTML] Organ-on-a-chip microengineering for bio-mimicking disease models and revolutionizing drug discovery

T Ahmed - Biosensors and Bioelectronics: X, 2022 - Elsevier
The core of the drug research and screening processes is predicting the effect of drugs prior
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …

Removal of per-and polyfluoroalkyl substances (PFAS) from wastewater using the hydrodynamic cavitation on a chip concept

FR Talabazar, C Baresel, R Ghorbani, I Tzanakis… - Chemical Engineering …, 2024 - Elsevier
The elimination of micropollutants such as highly fluorinated substances, including per-and
polyfluoroalkyl substances (PFAS), in wastewater treatment plants has been receiving …

Fundamentals, biomedical applications and future potential of micro-scale cavitation-a review

SS Sarraf, FR Talabazar, I Namli, M Maleki… - Lab on a Chip, 2022 - pubs.rsc.org
Thanks to the developments in the area of microfluidics, the cavitation-on-a-chip concept
enabled researchers to control and closely monitor the cavitation phenomenon in micro …

[HTML][HTML] Cavitating flows in microchannel with rough wall using a modified microscale cavitation model

XY Duan, BH Huang, YX Zhu, X Song, CY Zhu… - Case Studies in Thermal …, 2023 - Elsevier
Cavitation can induce drastic disruption and significantly enhance heat transfer, especially
in microchannels. However, due to the scale effect, the cavitation characteristics in micro …

[HTML][HTML] Investigation of hydrodynamic cavitation induced reactive oxygen species production in microchannels via chemiluminescent luminol oxidation reactions

D Podbevšek, G Ledoux, M Dular - Water research, 2022 - Elsevier
Hydrodynamic cavitation was evaluated for its reactive oxygen species production in several
convergent-divergent microchannel at the transition from micro to milli scale. Channel widths …

Chemical effects in “hydrodynamic cavitation on a chip”: The role of cavitating flow patterns

FR Talabazar, AS Aghdam, M Jafarpour… - Chemical Engineering …, 2022 - Elsevier
Amongst the advanced oxidation processes (AOPs), hydrodynamic cavitation (HC) has
emerged as one of the most cost-efficient, simple and ecologically friendly approaches in the …

On the application of hydrodynamic cavitation on a chip in cellular injury and drug delivery

I Namli, Z Karavelioglu, SS Sarraf, AS Aghdam… - Lab on a Chip, 2023 - pubs.rsc.org
Hydrodynamic cavitation (HC) is a phase change phenomenon, where energy release in a
fluid occurs upon the collapse of bubbles, which form due to the low local pressures. During …

Massively parallel direct writing of nanoapertures using multi-optical probes and super-resolution near-fields

C Park, S Hwang, D Kim, N Won, R Han… - Microsystems & …, 2022 - nature.com
Laser direct-writing enables micro and nanoscale patterning, and is thus widely used for
cutting-edge research and industrial applications. Various nanolithography methods, such …

Quantitative Evaluation of Submerged Cavitation Jet Performance Based on Image Processing Method

X Zhong, J Dong, R Meng, M Liu, X Pan - Journal of Marine Science and …, 2022 - mdpi.com
The submerged cavitation jet is suitable for ocean engineering activities such as ship fouling
cleaning, organic wastewater treatment, offshore oil drilling, and natural gas hydrate …