The past several years have witnessed the emergence of a new world of nucleic-acid-based
architectures with highly predictable and programmable self-assembly properties. For …

Nearly two decades after Westhof and Michel first proposed that RNA tetraloops may interact
with distal helices, tetraloop–receptor interactions have been recognized as ubiquitous …

One challenge in supramolecular chemistry is the design of versatile, self-assembling
building blocks to attain total control of arrangement of matter at a molecular level. We have …

RNA is an attractive biopolymer for nanodesign of self-assembling particles for
nanobiotechnology and synthetic biology. Here, we experimentally characterize by …

Fundamental control over supra-molecular self-assembly for organization of matter on the
nano-scale is a major objective of nanoscience and nanotechnology.'RNA tectonics' is the …

Arbitrary manipulation of molecular recognition at the atomic level has many applications.
However, systematic design and de novo synthesis of an artificial enzyme based on such …

In vitro selection of functional RNAs from large random sequence pools has led to the
identification of many ligand-binding and catalytic RNAs. However, the structural diversity in …

Association between RNAs with preprogrammed molecular recognition units can be
quantified by using cationic, water-soluble conjugated polymers. The method uses a …

RNA, which acts as a medium for transmitting genetic information, plays a variety of roles in
a cell. As with proteins, elucidation of the three‐dimensional (3D) structures of RNAs is …

We report herein the synthesis and DNA/RNA binding properties of bPNA+, a new variant of
bifacial peptide nucleic acid (bPNA) that binds oligo T/U nucleic acids to form triplex hybrids …