As the global population ages, bone‐related diseases have increasingly become a major
social problem threatening human health. Exosomes, as natural cell products, have been …

State-of-the-art bioactive hydrogels can easily and efficiently be formed by enzyme-
catalyzed mild-crosslinking reactions in situ. Yet this cell-friendly and substrate-specific …

Three-dimensional printing with Digital Lighting Processing (DLP) printer has come into the
new wave in the tissue engineering for regenerative medicine. Especially for the clinical …

OBJECTIVE: Three-dimensional (3D) cultures are widely used to redifferentiate
chondrocytes. However, the rationale behind the choice for 3D above two-dimensional (2D) …

In the context of OA disease, NF-κB transcription factors can be triggered by a host of stress-
related stimuli including pro-inflammatory cytokines, excessive mechanical stress and ECM …

Cartilage tissue engineering is emerging as a technique for the regeneration of cartilage
tissue damaged due to disease or trauma. Since cartilage lacks regenerative capabilities, it …

Healing articular cartilage remains a significant clinical challenge because of its limited self‐
healing capacity. While delivery of autologous chondrocytes to cartilage defects has …

Hyaline articular cartilage, the load-bearing tissue of the joint, has very limited repair and
regeneration capacities. The lack of efficient treatment modalities for large chondral defects …

Biomechanical cues such as shear stress, stretching, compression, and matrix elasticity are
vital in the establishment of next generation physiological in vitro tissue models. Matrix …

Chondrocytes are the exclusive cells residing in cartilage and maintain the functionality of
cartilage tissue. Series of biocomponents such as different growth factors, cytokines, and …