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Increasing confidence of allele calls with molecular counting
J Casbon, S Brenner, R Osborne… - US Patent …, 2013 - Google Patents
Aspects of the present invention include methods and com positions for determining the
number of individual poly nucleotide molecules originating from the same genomic region of …
number of individual poly nucleotide molecules originating from the same genomic region of …
L-ribo-LNA analogues
J Wengel - US Patent 7,053,207, 2006 - Google Patents
Provided are L-ribo bicyclic nucleotide compounds as well as syntheses of Such
compounds. The nucleoside com pounds of the invention are useful in forming oligonucle …
compounds. The nucleoside com pounds of the invention are useful in forming oligonucle …
Oligonucleotide analogues
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
27574410&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
27574410&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Modified polynucleotides for the production of biologics and proteins associated with human disease
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49235350&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
49235350&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Artificial nucleic acids of no bond crosslinkage type
T Imanishi, S Obika, K Miyashita - US Patent 7,427,672, 2008 - Google Patents
An oligonucleotide analogue useful for the antisense method, etc., having excellent enzyme
resistance, having potent selec tive binding a? inity for single-stranded RNA, and further …
resistance, having potent selec tive binding a? inity for single-stranded RNA, and further …
Oligonucleotide analogues
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H](O)[C@@ H](CO) O [C@@ H] 1N1C (N= CNC2= O)= C2N= C1 UGQMRVRMYYASKQ …
H](O)[C@@ H](CO) O [C@@ H] 1N1C (N= CNC2= O)= C2N= C1 UGQMRVRMYYASKQ …
Multi-primer amplification method for barcoding of target nucleic acids
A May, P Chen, J Wang, F Kaper… - US Patent 8,691,509, 2014 - Google Patents
B01L3/5027—Containers for the purpose of retaining a material to be analysed, eg test
tubes with fluid transport, eg in multi-compartment structures by integrated microfluidic …
tubes with fluid transport, eg in multi-compartment structures by integrated microfluidic …
Detection of nucleic acids
Q Nguyen, Y Ma, A Lin, S Levinson, C Lai - US Patent 9,273,349, 2016 - Google Patents
This invention provides compositions, methods, and systems for characterizing, resolving,
and quantitating single stranded and double stranded DNA and RNA in-situ. Paired sense …
and quantitating single stranded and double stranded DNA and RNA in-situ. Paired sense …
Nucleoside and oligonucleotide analogues
M Kaneko, K Morita, T Imanishi - US Patent 7,314,923, 2008 - Google Patents
US7314923B2 - Nucleoside and oligonucleotide analogues - Google Patents
US7314923B2 - Nucleoside and oligonucleotide analogues - Google Patents Nucleoside …
US7314923B2 - Nucleoside and oligonucleotide analogues - Google Patents Nucleoside …
Increasing dynamic range for identifying multiple epitopes in cells
GP Nolan - US Patent 10,174,310, 2019 - Google Patents
the present invention relates in part to the detection, identification, and quantification of
individual target molecules in single cells of a complex cell population while retaining cell …
individual target molecules in single cells of a complex cell population while retaining cell …