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Multifunctional role of exosomes in viral diseases: From transmission to diagnosis and therapy
Efforts to discover antiviral drugs and diagnostic platforms have intensified to an
unprecedented level since the outbreak of COVID-19. Nano-sized endosomal vesicles …
unprecedented level since the outbreak of COVID-19. Nano-sized endosomal vesicles …
From conventional to microfluidic: progress in extracellular vesicle separation and individual characterization
Extracellular vesicles (EVs) are nanoscale membrane vesicles, which contain a wide variety
of cargo such as proteins, miRNAs, and lipids. A growing body of evidence suggests that …
of cargo such as proteins, miRNAs, and lipids. A growing body of evidence suggests that …
An electrochemical aptasensor for exosomes based on strand displacement amplification and hybridization chain reaction amplification
J Zhang, J Chen, Q **e, Z Chu, F Zhang… - Sensors and Actuators B …, 2023 - Elsevier
Exosomes are lipid bilayer vesicles, relating to the happening and progress of cancer.
However, exploring reliable, convenient and sensitive exosomes detection methods in early …
However, exploring reliable, convenient and sensitive exosomes detection methods in early …
Accurate and portable tumor exosomes detection based on manganese dioxide and aptamer-functionalized fluorescent microspheres mediated dual-mode lateral …
J Chen, J Guo, M Hu, Y Wang, F Hua, HM Meng… - Sensors and Actuators B …, 2024 - Elsevier
As biomarkers for liquid biopsy, tumor exosomes play a key role in the early tumor diagnosis
and postoperative monitoring. However, the accurate and portable detection of exosomes …
and postoperative monitoring. However, the accurate and portable detection of exosomes …
Microsphere mediated exosome isolation and ultra-sensitive detection on a dielectrophoresis integrated microfluidic device
W Zhao, L Zhang, Y Ye, Y Li, X Luan, J Liu, J Cheng… - Analyst, 2021 - pubs.rsc.org
Tumor-derived exosomes have been recognized as potential biomarkers for cancer
diagnosis because they are actively involved in cancer progression and metastasis …
diagnosis because they are actively involved in cancer progression and metastasis …
In Situ, Fusion-Free, Multiplexed Detection of Small Extracellular Vesicle miRNAs for Cancer Diagnostics
F Zhou, L Pan, X Ma, J Ye, Z Xu, C Yuan… - Analytical …, 2024 - ACS Publications
Tumor-derived small extracellular vesicle (sEV) microRNAs (miRNAs) are emerging
biomarkers for cancer diagnostics. Conventional sEV miRNA detection methods necessitate …
biomarkers for cancer diagnostics. Conventional sEV miRNA detection methods necessitate …
Aptamer-based signal amplification strategies coupled with microchips for high-sensitivity bioanalytical applications: a review
R Xu, Y Cheng, X Li, Z Zhang, M Zhu, X Qi, L Chen… - Analytica Chimica …, 2022 - Elsevier
With their advantages in specificity, high stability and easy screening, aptamers are
becoming increasingly popular recognition elements for biosensor platforms. At the same …
becoming increasingly popular recognition elements for biosensor platforms. At the same …
Current progress and prospect of microfluidic-based exosome investigation
YK Wang, YR Bao, YX Liang, YJ Chen… - TrAC Trends in …, 2023 - Elsevier
Exosomes, nanoscale extracellular vesicles (≈ 30–150 nm diameter), are released by a
variety of cells and packaged with substantial information from origin cells for intercellular …
variety of cells and packaged with substantial information from origin cells for intercellular …
Microfluidic Device-Based In Vivo Detection of PD-L1-Positive Small Extracellular Vesicles and Its Application for Tumor Monitoring
XZ Cong, J Feng, HJ Zhang, LZ Zhang, TY Lin… - Analytical …, 2024 - ACS Publications
Liquid biopsy is of great significance in tumor early diagnosis and treatment stratification. PD-
L1-positive small extracellular vesicles (PD-L1+ sEVs) are closely related to tumor growth …
L1-positive small extracellular vesicles (PD-L1+ sEVs) are closely related to tumor growth …
Predictive analysis in oral cancer immunotherapy: profiling dual PD-L1-positive extracellular vesicle subtypes with step-wedge microfluidic chips
ZL Yu, ZY Wu, XC Liu, CX Ji, X Wang, QY Fu… - Analytical …, 2024 - ACS Publications
PD-L1-positive extracellular vesicles (PD-L1+ EVs) play a pivotal role as predictive
biomarkers in cancer immunotherapy. These vesicles, originating from immune cells (I-PD …
biomarkers in cancer immunotherapy. These vesicles, originating from immune cells (I-PD …