The clinical efficacy of antiretroviral therapy in NeuroAIDS is primarily limited by the low
perfusion of the drug to the brain. The objective of the current investigation was to design …

Being a biopharmaceutics classification system class II drug, the absorption of sertraline
from the gut is mainly limited by its poor aqueous solubility. The objective of this …

Recently, the co-crystallization of pharmaceutical drugs is gaining consideration because it
is an environmentally friendly and potentially effective technique to improve the solubility …

Pulsatile drug delivery systems have drawn attention in contemporary research for
designing chronotherapeutic systems. The current work aims to design pulsatile ketorolac …

Rivaroxaban (RXN) finds use in the management of pulmonary embolism and deep vein
thrombosis. Its poor solubility (5–7 µg/mL) and P-gp-mediated efflux from intestinal lining …

Being a candidate of BCS class II, dolutegravir (DTG), a recently approved antiretroviral
drug, possesses solubility issues. The current research was aimed to improve the solubility …

The objective of the current study is to evaluate the prospective of liquisolid formulation to
improve the dissolution rate of ketoprofen and thereby the bioavailability. Different batches …

Liquisolid systems are a novel, promising platform for the production of solid dosage forms
with a high liquid content, ie dispersion of the drug in a suitable, hydrophilic, non-volatile …

Antifungal therapy is causing an alarming drug resistance problem during the treatment of
Vaginal Candidiasis and also many of the antifungal vaginal marketed formulations have …

Background Curcumin, a natural polyphenol from Curcuma longa, is known to possess
diversified pharmacological roles including anti-inflammatory, antioxidant, antiproliferative …