The agenda for familial hypercholesterolemia: a scientific statement from the American Heart Association

SS Gidding, M Ann Champagne, SD de Ferranti… - Circulation, 2015 - ahajournals.org
2168 Circulation December 1, 2015 sufficient evidence for health benefit exists to implement
case finding via family history–based screening, cascade screening, or other strategies …

Defining severe familial hypercholesterolaemia and the implications for clinical management: a consensus statement from the International Atherosclerosis Society …

RD Santos, SS Gidding, RA Hegele… - The lancet Diabetes & …, 2016 - thelancet.com
Familial hypercholesterolaemia is common in individuals who had a myocardial infarction at
a young age. As many as one in 200 people could have heterozygous familial …

[HTML][HTML] National Lipid Association recommendations for patient-centered management of dyslipidemia: part 2

TA Jacobson, KC Maki, CE Orringer, PH Jones… - Journal of clinical …, 2015 - Elsevier
Abstract An Expert Panel convened by the National Lipid Association previously developed
a consensus set of recommendations for the patient-centered management of dyslipidemia …

Evinacumab for pediatric patients with homozygous familial hypercholesterolemia

A Wiegman, S Greber-Platzer, S Ali, MD Reijman… - Circulation, 2024 - ahajournals.org
BACKGROUND: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic
disorder characterized by severely elevated low-density lipoprotein cholesterol (LDL-C) …

Treatment gaps in adults with heterozygous familial hypercholesterolemia in the United States: data from the CASCADE-FH registry

EM Degoma, ZS Ahmad, EC O'Brien… - Circulation …, 2016 - ahajournals.org
Background—Cardiovascular disease burden and treatment patterns among patients with
familial hypercholesterolemia (FH) in the United States remain poorly described. In 2013 …

Prevalence and predictors of cholesterol screening, awareness, and statin treatment among US adults with familial hypercholesterolemia or other forms of severe …

EM Bucholz, AM Rodday, K Kolor, MJ Khoury… - Circulation, 2018 - ahajournals.org
Background: Familial hypercholesterolemia (FH) and other extreme elevations in low-
density lipoprotein cholesterol significantly increase the risk of atherosclerotic …

Familial hypercholesterolemia

VE Bouhairie, AC Goldberg - Endocrinology and Metabolism …, 2016 - endo.theclinics.com
Familial hypercholesterolemia (FH) is an inherited condition resulting in high levels of low-
density lipoprotein cholesterol (LDL-C) and increased risk of premature cardiovascular …

Familial hypercholesterolemia and elevated lipoprotein (a): double heritable risk and new therapeutic opportunities

A Vuorio, GF Watts, WJ Schneider… - Journal of internal …, 2020 - Wiley Online Library
There is compelling evidence that the elevated plasma lipoprotein (a)[Lp (a)] levels increase
the risk of atherosclerotic cardiovascular disease (ASCVD) in the general population. Like …

Mipomersen and its use in familial hypercholesterolemia

JS Parham, AC Goldberg - Expert opinion on pharmacotherapy, 2019 - Taylor & Francis
ABSTRACT Introduction: Familial Hypercholesterolemia (FH) is an inherited disorder
characterized by a defect in the binding and internalization of low-density lipoprotein (LDL) …

Cholesterol screening and treatment practices and preferences: a survey of United States pediatricians

SD de Ferranti, AM Rodday, SK Parsons, WL Cull… - The Journal of …, 2017 - Elsevier
Objectives To determine pediatricians' practices, attitudes, and barriers regarding screening
for and treatment of pediatric dyslipidemias in 9-to 11-year-olds and 17-to 21-year-olds …