Phosphodiesterase type 5 (PDE5) inhibitors such as Viagra®(sildenafil citrate) have
demonstrated efficacy in the treatment of erectile dysfunction (ED) by inducing cyclic …

Introduction: In men, lower urinary tract symptoms (LUTS) are primarily attributed to benign
prostatic hyperplasia (BPH). Therapeutic options are targeted to relax prostate smooth …

Sildenafil citrate, a selective oral phosphodiesterase 5 inhibitor, is a widely used drug for
erectile dysfunction that acts by elevating cGMP levels and causing smooth muscle …

Retinitis Pigmentosa (RP) reflects a range of inherited retinal disorders which involve
photoreceptor degeneration and retinal pigmented epithelium dysfunction. Despite the …

The retina is an easily accessible out-pouching of the central nervous system (CNS) and
thus lends itself to being a biomarker of the brain. More specifically, the presence of …

Purpose The phosphodiesterase inhibitor sildenafil is a promising treatment for
neurodegenerative disease, but it can cause oxidative stress in photoreceptors ex vivo and …

Ocular neovascularization is a common pathological feature in diabetic retinopathy and
neovascular age-related macular degeneration that can lead to severe vision loss. We …

Background Sildenafil citrate (SC) attenuates endothelial dysfunction. However, its effects
on diabetic retinopathy (DR), which is mainly a microvascular disease, remain unclear …

Abstract Membrane Protein Palmitoylated 5 (MPP5) is a highly conserved apical complex
protein essential for cell polarity, fate and survival. Defects in cell polarity are associated with …

Methods: Single retrospective case report. Results: A 31-year-old white man with no medical
history presented with complaints of bilateral multicolored photopsias and erythropsia (red …