Innovative and rapid antimicrobial susceptibility testing systems

A van Belkum, CAD Burnham, JWA Rossen… - Nature Reviews …, 2020 - nature.com
Antimicrobial resistance (AMR) is a major threat to human health worldwide, and the rapid
detection and quantification of resistance, combined with antimicrobial stewardship, are key …

Emerging technologies for antibiotic susceptibility testing

B Behera, GKA Vishnu, S Chatterjee… - Biosensors and …, 2019 - Elsevier
Superbugs such as infectious bacteria pose a great threat to humanity due to an increase in
bacterial mortality leading to clinical treatment failure, lengthy hospital stay, intravenous …

Adaptable microfluidic system for single-cell pathogen classification and antimicrobial susceptibility testing

H Li, P Torab, KE Mach, C Surrette… - Proceedings of the …, 2019 - National Acad Sciences
Infectious diseases caused by bacterial pathogens remain one of the most common causes
of morbidity and mortality worldwide. Rapid microbiological analysis is required for prompt …

Emerging microtechnologies and automated systems for rapid bacterial identification and antibiotic susceptibility testing

Y Li, X Yang, W Zhao - SLAS TECHNOLOGY: Translating …, 2017 - journals.sagepub.com
Rapid bacterial identification (ID) and antibiotic susceptibility testing (AST) are in great
demand due to the rise of drug-resistant bacteria. Conventional culture-based AST methods …

Advances in antimicrobial resistance monitoring using sensors and biosensors: A review

EC Reynoso, S Laschi, I Palchetti, E Torres - Chemosensors, 2021 - mdpi.com
The indiscriminate use and mismanagement of antibiotics over the last eight decades have
led to one of the main challenges humanity will have to face in the next twenty years in terms …

Reliable and reusable whole polypropylene plastic microfluidic devices for a rapid, low-cost antimicrobial susceptibility test

H Sun, CW Chan, Y Wang, X Yao, X Mu, X Lu, J Zhou… - Lab on a Chip, 2019 - pubs.rsc.org
Using an antimicrobial susceptibility test (AST) as an example, this work demonstrates a
practical method to fabricate microfluidic chips entirely from polypropylene (PP) and the …

Rapid Electrochemical Detection of Bacterial Sepsis in Cirrhotic Patients: A Microscaffold-Based Approach for Early Intervention

M Kaur, SH Bhat, R Tiwari, P Kale, DM Tripathi… - Analytical …, 2024 - ACS Publications
Sepsis is a dysregulated inflammatory response leading to multiple organ failure. Current
methods of sepsis detection are time-consuming, involving nonspecific clinical signs …

Unraveling antimicrobial susceptibility of bacterial networks on micropillar architectures using intrinsic phase-shift spectroscopy

H Leonard, S Halachmi, N Ben-Dov, O Nativ, E Segal - ACS nano, 2017 - ACS Publications
With global antimicrobial resistance becoming increasingly detrimental to society, improving
current clinical antimicrobial susceptibility testing (AST) is crucial to allow physicians to …

Bacterial growth sensing in microgels using pH-dependent fluorescence emission

A Chandra, N Singh - Chemical Communications, 2018 - pubs.rsc.org
We report the development of a platform for sensing bacterial growth by observing pH
change via a change in fluorescence. While the platform allows for the rapid detection of …

Microfluidic detection of movements of Escherichia coli for rapid antibiotic susceptibility testing

V Kara, C Duan, K Gupta, S Kurosawa… - Lab on a Chip, 2018 - pubs.rsc.org
Various nanomechanical movements of bacteria provide a signature of bacterial viability.
Most notably, bacterial movements have been observed to subside rapidly and dramatically …