The paradox of muscle hypertrophy in muscular dystrophy

JN Kornegay, MK Childers, DJ Bogan… - Physical Medicine …, 2012 - pmr.theclinics.com
Mutations in the human dystrophin gene cause 2 clinical phenotypes, Duchenne muscular
dystrophy (DMD) and Becker muscular dystrophy (BMD), distinguished principally based on …

Introduced herbivores restore Late Pleistocene ecological functions

EJ Lundgren, D Ramp, J Rowan, O Middleton… - Proceedings of the …, 2020 - pnas.org
Large-bodied mammalian herbivores dominated Earth's terrestrial ecosystems for several
million years before undergoing substantial extinctions and declines during the Late …

Developmental constraints on behavioural flexibility

KE Holekamp, EM Swanson… - … Transactions of the …, 2013 - royalsocietypublishing.org
We suggest that variation in mammalian behavioural flexibility not accounted for by current
socioecological models may be explained in part by developmental constraints. From our …

Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs

J Lopez-Rios, A Duchesne, D Speziale, G Andrey… - Nature, 2014 - nature.com
The large spectrum of limb morphologies reflects the wide evolutionary diversification of the
basic pentadactyl pattern in tetrapods. In even-toed ungulates (artiodactyls, including cattle) …

Incomplete convergence of gliding mammal skeletons

DM Grossnickle, M Chen, JGA Wauer, SK Pevsner… - …, 2020 - academic.oup.com
Ecology and biomechanics play central roles in the generation of phenotypic diversity. When
unrelated taxa invade a similar ecological niche, biomechanical demands can drive …

A multivariate approach to infer locomotor modes in Mesozoic mammals

M Chen, GP Wilson - Paleobiology, 2015 - cambridge.org
Ecomorphological diversity of Mesozoic mammals was presumably constrained by selective
pressures imposed by contemporary vertebrates. In accordance, Mesozoic mammals for a …

Musculoskeletal modeling of sprawling and parasagittal forelimbs provides insight into synapsid postural transition

RJ Brocklehurst, P Fahn-Lai, S Regnault, SE Pierce - Iscience, 2022 - cell.com
The sprawling–parasagittal postural shift was a major transition during synapsid evolution,
underpinned by reorganization of the forelimb, and considered key to mammalian ecological …

A systematic comparative description of extant turtle humeri, with comments on humerus disparity and evolution based on fossil comparisons

G Hermanson, FAM Arnal, T Szczygielski… - The Anatomical …, 2024 - Wiley Online Library
The humerus is central for locomotion in turtles as quadrupedal animals. Osteological
variation across testudine clades remains poorly documented. Here, we systematically …

Mammalian forelimb evolution is driven by uneven proximal-to-distal morphological diversity

PS Rothier, AC Fabre, J Clavel, RBJ Benson, A Herrel - Elife, 2023 - elifesciences.org
Vertebrate limb morphology often reflects the environment due to variation in locomotor
requirements. However, proximal and distal limb segments may evolve differently from one …

The fossil record of appendicular muscle evolution in Synapsida on the line to mammals: Part I—Forelimb

PJ Bishop, SE Pierce - The Anatomical Record, 2024 - Wiley Online Library
This paper is the first in a two‐part series that charts the evolution of appendicular
musculature along the mammalian stem lineage, drawing upon the exceptional fossil record …