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The paradox of muscle hypertrophy in muscular dystrophy
Mutations in the human dystrophin gene cause 2 clinical phenotypes, Duchenne muscular
dystrophy (DMD) and Becker muscular dystrophy (BMD), distinguished principally based on …
dystrophy (DMD) and Becker muscular dystrophy (BMD), distinguished principally based on …
Introduced herbivores restore Late Pleistocene ecological functions
Large-bodied mammalian herbivores dominated Earth's terrestrial ecosystems for several
million years before undergoing substantial extinctions and declines during the Late …
million years before undergoing substantial extinctions and declines during the Late …
Developmental constraints on behavioural flexibility
We suggest that variation in mammalian behavioural flexibility not accounted for by current
socioecological models may be explained in part by developmental constraints. From our …
socioecological models may be explained in part by developmental constraints. From our …
Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs
The large spectrum of limb morphologies reflects the wide evolutionary diversification of the
basic pentadactyl pattern in tetrapods. In even-toed ungulates (artiodactyls, including cattle) …
basic pentadactyl pattern in tetrapods. In even-toed ungulates (artiodactyls, including cattle) …
Incomplete convergence of gliding mammal skeletons
Ecology and biomechanics play central roles in the generation of phenotypic diversity. When
unrelated taxa invade a similar ecological niche, biomechanical demands can drive …
unrelated taxa invade a similar ecological niche, biomechanical demands can drive …
A multivariate approach to infer locomotor modes in Mesozoic mammals
Ecomorphological diversity of Mesozoic mammals was presumably constrained by selective
pressures imposed by contemporary vertebrates. In accordance, Mesozoic mammals for a …
pressures imposed by contemporary vertebrates. In accordance, Mesozoic mammals for a …
Musculoskeletal modeling of sprawling and parasagittal forelimbs provides insight into synapsid postural transition
The sprawling–parasagittal postural shift was a major transition during synapsid evolution,
underpinned by reorganization of the forelimb, and considered key to mammalian ecological …
underpinned by reorganization of the forelimb, and considered key to mammalian ecological …
A systematic comparative description of extant turtle humeri, with comments on humerus disparity and evolution based on fossil comparisons
The humerus is central for locomotion in turtles as quadrupedal animals. Osteological
variation across testudine clades remains poorly documented. Here, we systematically …
variation across testudine clades remains poorly documented. Here, we systematically …
Mammalian forelimb evolution is driven by uneven proximal-to-distal morphological diversity
Vertebrate limb morphology often reflects the environment due to variation in locomotor
requirements. However, proximal and distal limb segments may evolve differently from one …
requirements. However, proximal and distal limb segments may evolve differently from one …
The fossil record of appendicular muscle evolution in Synapsida on the line to mammals: Part I—Forelimb
This paper is the first in a two‐part series that charts the evolution of appendicular
musculature along the mammalian stem lineage, drawing upon the exceptional fossil record …
musculature along the mammalian stem lineage, drawing upon the exceptional fossil record …