The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

SARS-CoV-2 variants, vaccines, and host immunity

P Mistry, F Barmania, J Mellet, K Peta… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new beta coronavirus
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …

Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic

SSA Karim, QA Karim - The lancet, 2021 - thelancet.com
SARS-CoV-2 variant of concern (VoC), omicron, 2 was reported. Omicron emerged in a
COVID-19-weary world in which anger and frustration with the pandemic are rife amid …

[HTML][HTML] Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2

P Han, L Li, S Liu, Q Wang, D Zhang, Z Xu, P Han, X Li… - Cell, 2022 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic continues worldwide with
many variants arising, some of which are variants of concern (VOCs). A recent VOC, omicron …

Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial

PB Gilbert, DC Montefiori, AB McDermott, Y Fong… - Science, 2022 - science.org
In the coronavirus efficacy (COVE) phase 3 clinical trial, vaccine recipients were assessed
for neutralizing and binding antibodies as correlates of risk for COVID-19 disease and as …

Understanding COVID-19 vaccine hesitancy

S Machingaidze, CS Wiysonge - Nature medicine, 2021 - nature.com
Understanding COVID-19 vaccine hesitancy | Nature Medicine Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Immunological mechanisms of vaccine-induced protection against COVID-19 in humans

M Sadarangani, A Marchant… - Nature Reviews …, 2021 - nature.com
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …

SARS-CoV-2 variants in patients with immunosuppression

L Corey, C Beyrer, MS Cohen… - … England Journal of …, 2021 - Mass Medical Soc
SARS-CoV-2 Variants in Patients with Immunosuppression | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …

A paper-based assay for the colorimetric detection of SARS-CoV-2 variants at single-nucleotide resolution

T Zhang, R Deng, Y Wang, C Wu, K Zhang… - Nature Biomedical …, 2022 - nature.com
The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
highlighted the need for versatile diagnostic assays that can discriminate among emerging …

A comprehensive review of COVID-19 virology, vaccines, variants, and therapeutics

L Forchette, W Sebastian, T Liu - Current medical science, 2021 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of
the coronavirus disease 2019 (COVID-19), has caused more than 179 million infections and …