Alzheimer's disease

JAS Lopez, HM González, GC Léger - Handbook of clinical neurology, 2019 - Elsevier
Alzheimer's disease (AD) dementia refers to a particular onset and course of cognitive and
functional decline associated with age together with a particular neuropathology. It was first …

On the path to 2025: understanding the Alzheimer's disease continuum

PS Aisen, J Cummings, CR Jack, JC Morris… - Alzheimer's research & …, 2017 - Springer
Basic research advances in recent years have furthered our understanding of the natural
history of Alzheimer's disease (AD). It is now recognized that pathophysiological changes …

Recommendations of the 5th Canadian Consensus Conference on the diagnosis and treatment of dementia

Z Ismail, SE Black, R Camicioli… - Alzheimer's & …, 2020 - Wiley Online Library
Abstract Since 1989, four Canadian Consensus Conferences on the Diagnosis and
Treatment of Dementia (CCCDTD) have provided evidence‐based dementia guidelines for …

Mini‐Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations

ST Creavin, S Wisniewski… - Cochrane Database …, 2016 - cochranelibrary.com
Background The Mini Mental State Examination (MMSE) is a cognitive test that is commonly
used as part of the evaluation for possible dementia. Objectives To determine the diagnostic …

Screening for cognitive impairment in older adults: updated evidence report and systematic review for the US Preventive Services Task Force

CD Patnode, LA Perdue, RC Rossom, MC Rushkin… - Jama, 2020 - jamanetwork.com
Importance Early identification of cognitive impairment may improve patient and caregiver
health outcomes. Objective To systematically review the test accuracy of cognitive screening …

Underdiagnosis of dementia: an observational study of patterns in diagnosis and awareness in US older adults

H Amjad, DL Roth, OC Sheehan, CG Lyketsos… - Journal of general …, 2018 - Springer
Background Many older adults living with dementia have not been formally diagnosed. Even
when clinicians document the diagnosis, patients and families may be unaware of the …

Dementia: What pharmacists need to know

S Duong, T Patel, F Chang - Canadian Pharmacists Journal …, 2017 - journals.sagepub.com
Dementia is a devastating disease that places a significant physical, emotional and financial
burden on patients, their caregivers and society. About 564,000 Canadians have dementia …

Artificial intelligence, speech, and language processing approaches to monitoring Alzheimer's disease: a systematic review

S De la Fuente Garcia, CW Ritchie… - Journal of Alzheimer's …, 2020 - content.iospress.com
Background: Language is a valuable source of clinical information in Alzheimer's disease,
as it declines concurrently with neurodegeneration. Consequently, speech and language …

Cognitive tests for the detection of mild cognitive impairment (MCI), the prodromal stage of dementia: Meta‐analysis of diagnostic accuracy studies

A Breton, D Casey… - International journal of …, 2019 - Wiley Online Library
Introduction Mild cognitive impairment (MCI) is regarded as a prodrome to dementia.
Various cognitive tests can help with diagnosis; meta‐analysis of diagnostic accuracy …

Dementia: timely diagnosis and early intervention

L Robinson, E Tang, JP Taylor - Bmj, 2015 - bmj.com
Dementia describes a clinical syndrome that encompasses difficulties in memory, language,
and behaviour that leads to impairments in activities of daily living. Alzheimer's disease is …