The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete ty** units (DTUs) …

Chagas disease, caused by the protozoan Trypanosoma cruzi, has a variable clinical
course, ranging from symptomless infection to severe chronic disease with cardiovascular or …

This report of a WHO Expert Committee reviews current knowledge of Chagas disease and
its pathogenesis discusses the causative parasite the triatomine vectors and the natural …

Genetic variation in Trypanosoma cruzi is likely a key determinant in transmission and
pathogenesis of Chagas disease. We have examined nine loci as markers for the extant T …

It has been proposed that isolates of Trypanosoma cruzi, the agent of American
trypanosomiasis, can be ordered into two primary phylogenetic lineages, first based on …

The intracellular protozoan parasite Trypanosoma cruzi is the causative agent of Chagas'
disease, a serious disorder that affects millions of people in Latin America. Despite the …

In the absence of a fossil record, theories relating to the evolution of protozoa have, for most
of the twentieth century, been based on morphological and life cycle data despite their …

Chagas disease caused by Trypanosoma cruzi is a complex disease that is endemic and an
important problem in public health in Latin America. The T. cruzi parasite is classified into six …

Abstract Human American trypanosomiasis or Chagas disease—named after Carlos
Chagas who first described it in 1909—exists only on the American continent. It is caused by …

The agent of Chagas disease, Trypanosoma cruzi, is divided into two highly divergent
genetic subgroups, lineages 1 and 2, which include all typed strains isolated from humans …