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Emerging neuroprotective strategies for the treatment of ischemic stroke: An overview of clinical and preclinical studies
Stroke is the leading cause of disability and thesecond leading cause of death worldwide.
With the global population aged 65 and over growing faster than all other age groups, the …
With the global population aged 65 and over growing faster than all other age groups, the …
MicroRNA delivery through nanoparticles
MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …
Progress in microRNA delivery
MicroRNAs (miRNAs) are non-coding endogenous RNAs that direct post-transcriptional
regulation of gene expression by several mechanisms. Activity is primarily through binding …
regulation of gene expression by several mechanisms. Activity is primarily through binding …
Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a
Long noncoding RNAs are involved in diseases including cancer. Here, we reported that
ANRIL (CDKN2B-AS1), a 3.8-kb long noncoding RNA, recruiting and binding to PRC2, was …
ANRIL (CDKN2B-AS1), a 3.8-kb long noncoding RNA, recruiting and binding to PRC2, was …
miRNAs inspirations in hepatocellular carcinoma: detrimental and favorable aspects of key performers
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related deaths
worldwide. HCC initiation, progression, and therapy failure are all influenced by various …
worldwide. HCC initiation, progression, and therapy failure are all influenced by various …
MicroRNAs as biomarkers for liver disease and hepatocellular carcinoma
CN Hayes, K Chayama - International journal of molecular sciences, 2016 - mdpi.com
Serum levels of liver enzymes, such as alanine transaminase, aspartate transaminase, and
α-fetoprotein, provide insight into liver function and are used during treatment of liver …
α-fetoprotein, provide insight into liver function and are used during treatment of liver …
[HTML][HTML] Targeting EGFR/PI3K/AKT/mTOR signaling in hepatocellular carcinoma
J Bang, M Jun, S Lee, H Moon, SW Ro - Pharmaceutics, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) poses a significant global health concern, with its
incidence steadily increasing. The development of HCC is a multifaceted, multi-step process …
incidence steadily increasing. The development of HCC is a multifaceted, multi-step process …
MicroRNAs in the pathogenesis of hepatocellular carcinoma: a review
A Morishita, K Oura, T Tadokoro, K Fujita, J Tani… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is one of the most frequently occurring
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …
Non-coding RNA mediated regulation of PI3K/Akt pathway in hepatocellular carcinoma: therapeutic perspectives
Hepatocellular carcinoma (HCC) is among the primary reasons for fatalities caused by
cancer globally, highlighting the need for comprehensive knowledge of its molecular …
cancer globally, highlighting the need for comprehensive knowledge of its molecular …
Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway
Hypoxia activates autophagy, an evolutionarily conserved cellular catabolic process.
Dysfunction in the autophagy pathway has been implicated in an increasing number of …
Dysfunction in the autophagy pathway has been implicated in an increasing number of …