Mental disorders represent a worldwide public health concern. Psychotherapies and
pharmacotherapies are recommended as first line treatments. However, evidence has …

Background The benefits and safety of medications for attention-deficit hyperactivity disorder
(ADHD) remain controversial, and guidelines are inconsistent on which medications are …

Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on
how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered …

Methods This document presents the official recommendations of the AGA on the medical
management of moderate to severe luminal and fistulizing CD in adults. This guideline …

Importance Generalized anxiety disorder (GAD) is one of the most common mental disorders
in adults. Psychotherapies are among the most recommended treatments for GAD, but which …

Background Depressive disorders are common in children and adolescents.
Antidepressants, psychotherapies, and their combination are often used in routine clinical …

Background: Several pharmacologic options for type 2 diabetes are available. Purpose: To
compare benefits and harms of glucose-lowering drugs in adults with type 2 diabetes. Data …

(AGA) on the management of moderate to severe ulcerative colitis (UC). The guideline was
developed by the AGA Institute's Clinical Guidelines Committee and approved by the AGA …

Objective To compare the efficacy and discontinuation of augmentation agents in adult
patients with treatment-resistant depression (TRD). We conducted a systematic review and …

A systematic review and random-effects model network meta-analysis were conducted to
compare the efficacy, acceptability, tolerability, and safety of antidepressants to treat adults …