Autophagy and apoptosis: where do they meet?
Autophagy and apoptosis are two important cellular processes with complex and
intersecting protein networks; as such, they have been the subjects of intense investigation …
intersecting protein networks; as such, they have been the subjects of intense investigation …
LPS-induced cytokine production in human monocytes and macrophages
Lipopolysaccharide (LPS) from Gram-negative bacteria is one of the most potent innate
immune-activating stimuli known. Here we review the current understanding of LPS effects …
immune-activating stimuli known. Here we review the current understanding of LPS effects …
Gene therapies for cancer: strategies, challenges and successes
SK Das, ME Menezes, S Bhatia… - Journal of cellular …, 2015 - Wiley Online Library
Gene therapy, which involves replacement of a defective gene with a functional, healthy
copy of that gene, is a potentially beneficial cancer treatment approach particularly over …
copy of that gene, is a potentially beneficial cancer treatment approach particularly over …
GADD45 proteins: central players in tumorigenesis
RE Tamura, JF de Vasconcellos… - Current molecular …, 2012 - ingentaconnect.com
The Growth Arrest and DNA Damage-inducible 45 (GADD45) proteins have been implicated
in regulation of many cellular functions including DNA repair, cell cycle control, senescence …
in regulation of many cellular functions including DNA repair, cell cycle control, senescence …
IL-10 family of cytokines
R Sabat - Cytokine & growth factor reviews, 2010 - Elsevier
In 2001, six immune mediators (IL-10, IL-19, IL-20, IL-22, IL-24, and IL-26) were grouped
into the so-called IL-10 family of cytokines based on their similarities with respect to the …
into the so-called IL-10 family of cytokines based on their similarities with respect to the …
Autophagy: cancer's friend or foe?
The functional relevance of autophagy in tumor formation and progression remains
controversial. Autophagy can promote tumor suppression during cancer initiation and …
controversial. Autophagy can promote tumor suppression during cancer initiation and …
Targeting Mcl-1 for the therapy of cancer
Introduction: Human cancers are genetically and epigenetically heterogeneous and have
the capacity to commandeer a variety of cellular processes to aid in their survival, growth …
the capacity to commandeer a variety of cellular processes to aid in their survival, growth …
MDA-7/IL-24: multifunctional cancer killing cytokine
ME Menezes, S Bhatia, P Bhoopathi, SK Das… - Anticancer Genes, 2014 - Springer
First identified almost two decades ago as a novel gene differentially expressed in human
melanoma cells induced to terminally differentiate, MDA-7/IL-24 has since shown great …
melanoma cells induced to terminally differentiate, MDA-7/IL-24 has since shown great …
T helper 2 cell–directed immunotherapy eliminates precancerous skin lesions
T Oka, SS Smith, HG Son, T Lee, VS Oliver-Garcia… - The Journal of Clinical …, 2025 - jci.org
The continuous rise in skin cancer incidence highlights an imperative for improved skin
cancer prevention. Topical calcipotriol-plus–5-fluorouracil (calcipotriol-plus–5-FU) …
cancer prevention. Topical calcipotriol-plus–5-fluorouracil (calcipotriol-plus–5-FU) …
Oncolytic adenovirus complexes coated with lipids and calcium phosphate for cancer gene therapy
Oncolytic adenovirus (OncoAd) is a promising therapeutic agent for treating cancer.
However, the therapeutic potential of OncoAd is hindered by hepatic sequestration and the …
However, the therapeutic potential of OncoAd is hindered by hepatic sequestration and the …