Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …

Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …

Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress) …

This review focuses on the association between vascular calcification and arterial stiffness,
highlighting the important genetic factors, systemic and local microenvironmental signals …

Background The association between type 1 diabetes mellitus (T1DM) and specific
cardiovascular diseases (CVD) is uncertain. Furthermore, data on type 2 diabetes mellitus …

The view of atherosclerosis as an inflammatory disease has emerged from observations of
immune activation and inflammatory signalling in human atherosclerotic lesions, from the …

A non-resolving inflammation results in a chronic inflammatory response, characteristic of
atherosclerosis, abdominal aortic aneurysms and several other cardiovascular diseases …

Cardiovascular diseases represent a major cause of morbidity and mortality, necessitating
research to improve diagnostics, and to discover and test novel preventive and curative …

Mechanical forces are well known for modulating heart valve developmental programs. Yet,
it is still unclear how genetic programs and mechanosensation interact during heart valve …

Large aortic aneurysm and acute and chronic aortic dissection are pathologies of the aorta
requiring surgery. Recent advances in medical intervention have improved patient …