The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …

Mesenchymal stem cells (MSCs) are a heterogeneous subset of stromal stem cells that can
be isolated from many adult tissues. They can differentiate into cells of the mesodermal …

Chondral and osteochondral lesions due to injury or other pathology commonly result in the
development of osteoarthritis, eventually leading to progressive total joint destruction …

Bones play an important role in maintaining exercise and protecting organs. Bone defect, as
a common orthopedic disease in clinics, can cause tremendous damage with long treatment …

Ossification is a tightly regulated process, performed by specialized cells called osteoblasts.
Dysregulation of this process may cause inadequate or excessive mineralization of bones or …

Successful regeneration of large segmental bone defects remains a major challenge in
clinical orthopedics, thus it is of important significance to fabricate a suitable alternative …

Objective To review the basic scientific status of repair in articular cartilage tissue and to
assess the efficiency of current clinical therapies instigated for the treatment of structural …

This review discusses and summarizes the recent developments and advances in the use of
biodegradable materials for bone repair purposes. The choice between using degradable …

Calcium phosphates (CaPs) are biocompatible and biodegradable materials showing a
great promise in bone regeneration as good alternative to the use of auto-and allografts to …

Mesenchymal stem cells (MSCs) have been isolated from bone marrow, periosteum,
trabecular bone, adipose tissue, synovium, skeletal muscle and deciduous teeth. These …