The great plasticity of Schwann cells (SCs), the myelinating glia of the peripheral nervous
system (PNS), is a critical feature in the context of peripheral nerve regeneration following …

The remarkable plasticity of Schwann cells allows them to adopt the Remak (non-myelin)
and myelin phenotypes, which are specialized to meet the needs of small and large …

Schwann cells respond to nerve injury by cellular reprogramming that generates cells
specialized for promoting regeneration and repair. These repair cells clear redundant …

Schwann cell dedifferentiation from a myelinating to a progenitor-like cell underlies the
remarkable ability of peripheral nerves to regenerate following injury. However, the …

ABSTRACT RUNX transcription factors orchestrate many different aspects of biology,
including basic cellular and developmental processes, stem cell biology and tumorigenesis …

Repair Schwann cells play a critical role in orchestrating nerve repair after injury, but the
cellular and molecular processes that generate them are poorly understood. Here, we …

Myelination is essential for nervous system function. Schwann cells interact with neurons
and the basal lamina to myelinate axons using known receptors, signals and transcription …

Ferulic acid, a natural phytochemical has gained importance as a potential therapeutic
agent by virtue of its easy commercial availability, low cost and minimal side-effects. It is a …

Transcription factors are master regulators of various cellular processes under diverse
physiological and pathological conditions. Many transcription factors that are differentially …

Abstract Since Waller and Cajal in the nineteenth and early twentieth centuries, laboratory
traumatic peripheral nerve injury studies have provided great insight into cellular and …