Long-term outcomes of deep brain stimulation in Parkinson disease

P Limousin, T Foltynie - Nature Reviews Neurology, 2019 - nature.com
The efficacy of deep brain stimulation (DBS) for Parkinson disease (PD) is well established
for up to 1 or 2 years, but long-term outcome data are still limited. In this Review, we critically …

The future of stem cell therapies for Parkinson disease

M Parmar, S Grealish, C Henchcliffe - Nature Reviews Neuroscience, 2020 - nature.com
Cell-replacement therapies have long been an attractive prospect for treating Parkinson
disease. However, the outcomes of fetal tissue-derived cell transplants in individuals with …

Neuroprosthetics: from sensorimotor to cognitive disorders

A Gupta, N Vardalakis, FB Wagner - Communications biology, 2023 - nature.com
Neuroprosthetics is a multidisciplinary field at the interface between neurosciences and
biomedical engineering, which aims at replacing or modulating parts of the nervous system …

[HTML][HTML] Deep brain stimulation targets for treating depression

D Drobisz, A Damborská - Behavioural brain research, 2019 - Elsevier
Deep brain stimulation (DBS) is a new therapeutic approach for treatment-resistant
depression (TRD). There is a preliminary evidence of the efficacy and safety of DBS for TRD …

Deep brain stimulation in Parkinson disease: a meta-analysis of the long-term neuropsychological outcomes

M Bucur, C Papagno - Neuropsychology review, 2023 - Springer
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) or globus pallidum internus
(GPi) improves motor functions in patients with Parkinson's disease (PD) but may cause a …

Adverse events in deep brain stimulation: A retrospective long-term analysis of neurological, psychiatric and other occurrences

C Buhmann, T Huckhagel, K Engel, A Gulberti… - PloS one, 2017 - journals.plos.org
Background and objective The extent to which deep brain stimulation (DBS) can improve
quality of life may be perceived as a permanent trade-off between neurological …

Landscape and future directions of machine learning applications in closed-loop brain stimulation

AS Chandrabhatla, IJ Pomeraniec, TM Horgan… - NPJ Digital …, 2023 - nature.com
Brain stimulation (BStim) encompasses multiple modalities (eg, deep brain stimulation,
responsive neurostimulation) that utilize electrodes implanted in deep brain structures to …

Awake versus asleep deep brain stimulation for Parkinson's disease: a critical comparison and meta-analysis

AL Ho, R Ali, ID Connolly, JM Henderson… - Journal of Neurology …, 2018 - jnnp.bmj.com
Objective No definitive comparative studies of the efficacy of 'awake'deep brain stimulation
(DBS) for Parkinson's disease (PD) under local or general anaesthesia exist, and there …

Weight loss and malnutrition in patients with Parkinson's disease: current knowledge and future prospects

K Ma, N **ong, Y Shen, C Han, L Liu… - Frontiers in aging …, 2018 - frontiersin.org
Parkinson's Disease (PD) is currently considered a systemic neurodegenerative disease
manifested with not only motor but also non-motor symptoms. In particular, weight loss and …

Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: a meta-analysis of mood effects

T Cartmill, D Skvarc, R Bittar, J McGillivray… - Neuropsychology …, 2021 - Springer
This meta-analysis examines mood changes after bilateral subthalamic deep brain
stimulation (STN-DBS) in patients with Parkinson's disease (PD). Deep brain stimulation …