In the absence of effective interventions to prevent preterm births, improved survival of
infants who are born at the biological limits of viability has relied on advances in perinatal …

Formation of the human heart involves complex biological signals, interactions, specification
of myocardial progenitor cells, and heart tube loo**. To facilitate survival in the hypoxemic …

Objective To determine if preterm birth is associated with components of the metabolic
syndrome in adult life. Study design A structured literature search was performed using …

Background: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive
syndromes is a significant determinant of short-and long-term outcomes. Although …

In this review of 126 publications, we report that an overwhelming majority of adults born at
preterm gestations remain healthy and well. However, a small, but a significant fraction of …

Pulmonary hypertension (PH) describes heterogeneous population of patients with a mean
pulmonary arterial pressure> 20 mm Hg. Rarely, PH presents as a primary disorder but is …

Preterm birth survivors are at a higher risk of growth and developmental disabilities
compared to their term counterparts. Development of strategies to lower the complications of …

Background: In small clinical studies, preterm birth was associated with altered cardiac
structure and increased cardiovascular mortality in the young. Objectives: The goal of this …

Early life is an important window of opportunity to improve health across the full lifecycle. An
accumulating body of evidence suggests that exposure to adverse stressors during early life …

Rationale: Premature birth affects 10% of live births in the United States and is associated
with alveolar simplification and altered pulmonary microvascular development. However …