The emerging aptamer, developed through the systematic evolution of ligands by
exponential enrichment (SELEX) process, has revolutionized and facilitated the discoveries …

Aptamers are short, single-stranded oligonucleotides that bind to specific target molecules.
The shape-forming feature of single-stranded oligonucleotides provides high affinity and …

The origin of life is a fascinating, unresolved problem whose deciphering would have
important scientific, epistemological and social implications. Over time, philosophers and …

It is estimated that the human genome encodes 15% of proteins that are considered to be
disease-modifying. Only 2% of these proteins possess a druggable site that the approved …

Molecular imaging is revolutionizing the way we study the inner workings of the human
body, diagnose diseases, approach drug design, and assess therapies. The field as a whole …

SELEX stands for systematic evolution of ligands by exponential enrichment. This method,
described primarily in 1990 [Ellington, AD, Szostak, JW, 1990. In vitro selection of RNA …

Impedance biosensors are a class of electrical biosensors that show promise for point‐of‐
care and other applications due to low cost, ease of miniaturization, and label‐free …

In analogy to split-protein systems, which rely on the appropriate fragmentation of protein
domains, split aptamers made of two or more short nucleic acid strands have emerged as …

A novel concept to improve the catalytic functions of nucleic acids (DNAzymes) is
introduced. The method involves the conjugation of a DNA recognition sequence (aptamer) …

For many years, different probing techniques have mainly relied on antibodies for molecular
recognition. However, with the discovery of aptamers, this has changed. The science …