Using singlet oxygen to synthesize natural products and drugs
This Review describes singlet oxygen (1O2) in the organic synthesis of targets on possible
1O2 biosynthetic routes. The visible-light sensitized production of 1O2 is not only useful for …
1O2 biosynthetic routes. The visible-light sensitized production of 1O2 is not only useful for …
Continuous photo-oxidation in a vortex reactor: efficient operations using air drawn from the laboratory
We report the construction and use of a vortex reactor which uses a rapidly rotating cylinder
to generate Taylor vortices for continuous flow thermal and photochemical reactions. The …
to generate Taylor vortices for continuous flow thermal and photochemical reactions. The …
Applying green chemistry to the photochemical route to artemisinin
Artemisinin is an important antimalarial drug, but, at present, the environmental and
economic costs of its semi-synthetic production are relatively high. Most of these costs lie in …
economic costs of its semi-synthetic production are relatively high. Most of these costs lie in …
Furans and singlet oxygen–why there is more to come from this powerful partnership
The purpose of this article is to give a taste of just how powerful the union between furans
and photochemically-generated singlet oxygen is proving to be as a synthetic tool and to …
and photochemically-generated singlet oxygen is proving to be as a synthetic tool and to …
[HTML][HTML] Impact of continuous flow chemistry in the synthesis of natural products and active pharmaceutical ingredients
We present a comprehensive review of the advent and impact of continuous flow chemistry
with regard to the synthesis of natural products and drugs, important pharmaceutical …
with regard to the synthesis of natural products and drugs, important pharmaceutical …
Wireless μLED packed beds for scalable continuous multiphasic photochemistry
Photochemical and photocatalytic reactions are a powerful emerging tool in the green
synthesis of organic molecules. In contrast to thermochemical reactions, they promise …
synthesis of organic molecules. In contrast to thermochemical reactions, they promise …
Self-sensitized photooxidation of naphthols to naphthoquinones and the use of naphthoquinones as visible light photocatalysts in batch and continuous flow reactors
M Lancel, P Zimberlin, C Gomez, M Port… - The Journal of …, 2023 - ACS Publications
Visible light photooxidation of naphthols to produce naphthoquinones, such as the natural
product juglone, has been known for decades and has been widely utilized to benchmark …
product juglone, has been known for decades and has been widely utilized to benchmark …
Parallel microflow photochemistry: process optimization, scale-up, and library synthesis
A novel, multimicrocapillary flow reactor (MμCFR) was constructed and applied to a series of
sensitized photoadditions involving 2 (5 H)-furanones. The reactor allowed for rapid and …
sensitized photoadditions involving 2 (5 H)-furanones. The reactor allowed for rapid and …
Optimization of a scalable photochemical reactor for reactions with singlet oxygen
Oxygenation of α-pinene using photochemically generated singlet oxygen (1O2) was
studied in detail in several continuous flow photochemical reactors. Ferrioxalate actinometry …
studied in detail in several continuous flow photochemical reactors. Ferrioxalate actinometry …
A synergistic study on the synthesis of juglone via photooxidation in a UV–Vis LED based photomicroreactor
M Pasha, S Liu, M Shang, M Qiu, Y Su - Chemical Engineering Journal, 2022 - Elsevier
Photochemical transformations are mobilized by traceless photons of narrow or broad
visible light wavelength and have been proven as a green and sustainable synthesis route …
visible light wavelength and have been proven as a green and sustainable synthesis route …