Vibrational spectroscopic characterization and structural investigations of Cepharanthine, a natural alkaloid

S Celik, S Akyuz, AE Ozel - Journal of Molecular Structure, 2022 - Elsevier
Cepharanthine, a natural alkaloid obtained from the Stephania cepharantha Hayata plant,
that has antitumor, anti-inflammatory, antioxidative, antiparasitic, and antiviral properties …

Rotamer dynamics: analysis of rotamers in molecular dynamics simulations of proteins

Y Haddad, V Adam, Z Heger - Biophysical journal, 2019 - cell.com
Given by χ torsional angles, rotamers describe the side-chain conformations of amino acid
residues in a protein based on the rotational isomers (hence the word rotamer). Constructed …

The Genus Cladosporium: A Prospective Producer of Natural Products

Y Li, Y Wang, H Wang, T Shi, B Wang - International Journal of Molecular …, 2024 - mdpi.com
Cladosporium, a genus of ascomycete fungi in the Dematiaceae family, is primarily
recognized as a widespread environmental saprotrophic fungus or plant endophyte. Further …

Structural and vibrational investigations and molecular docking studies of a vinca alkoloid, vinorelbine

S Celik, S Akyuz, AE Ozel - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Vinorelbine, a vinca alkaloid, is an antimitotic drug that inhibits polymerisation process of
tubulins to microtubules, and is widely used in cancer chemotherapy. Due to the importance …

Shedding light into the biological activity of aminopterin, via molecular structural, docking, and molecular dynamics analyses

S Celik, G Yilmaz, S Akyuz, AE Ozel - Journal of Biomolecular …, 2024 - Taylor & Francis
In this study, the structural and anticancer properties of aminopterin, as well as its antiviral
characteristics, were elucidated. The preferred conformations of the title molecule were …

Structural and spectral analysis of anticancer active cyclo (Ala–His) dipeptide

S Celik, G Yilmaz, AE Ozel, S Akyuz - Journal of Biomolecular …, 2022 - Taylor & Francis
The theoretically possible most stable conformation of the cyclic dipeptide, which has a
significant anticancer activity, was examined by conformational analysis method and then by …

Vibrational and structural properties of L-Alanyl-L-Phenylalanine dipeptide by Raman spectroscopy, infrared and DFT calculations

CB Silva, JG da Silva Filho, GS Pinheiro… - Vibrational …, 2018 - Elsevier
A study of vibrational and structural properties of l-Alanyl-l-Phenylalanine hydrophobic
dipeptide (molecular formula C 12 H 16 N 2 O 3) is reported. The l-alanyl-l-phenylalanine is …

High-pressure studies on l, l-dileucine crystals by Raman spectroscopy and synchrotron X-ray diffraction combined with DFT calculations

CB Silva, JG da Silva Filho, GS Pinheiro… - … Acta Part A: Molecular …, 2020 - Elsevier
The vibrational properties of the dipeptide l-leucyl-l-leucine hydrate were investigated
through Raman and infrared spectroscopy. With the aid of first principle calculations using …

The Structural Characterisation and DFT-Aided Interpretation of Vibrational Spectra for Cyclo(l-Cys-d-Cys) Cyclic Dipeptide in a Solid State

M Witkowski, D Trzybiński, S Pawlędzio, K Woźniak… - Molecules, 2023 - mdpi.com
Cyclic dipeptides with two intramolecular peptide bonds forming a six-membered 2, 5-
diketopiperazine ring are gaining significant attention due to their biological and chemical …

New route for synthesis of 2-(2, 2-dimethoxyethyl)-1, 2, 3, 4, 5, 6-hexahydro-1, 5-methanoazocino [4, 3-b] indole and DFT investigation

N Uludağ, G Serdaroğlu - Heliyon, 2020 - cell.com
Abstract Development of efficient sequences for the synthesis of the title compound (2-(2, 2-
dimethoxyethyl)-1, 2, 3, 4, 5, 6-hexahydro-1, 5-methanoazocino [4, 3-b] indole)(7) was …