Respiratory syncytial virus (RSV) is an important etiological agent of respiratory infections,
particularly in children. Much information regarding the immune response to RSV comes …

Eosinophils are specialized white blood cells, which are involved in the pathology of diverse
allergic and nonallergic inflammatory diseases. Eosinophils are traditionally known as …

Background Respiratory syncytial virus (RSV) is the leading cause of viral lower respiratory
tract infection (LRTI) and hospitalization in infants. Mostly because of the incomplete …

The introduction of in vitro nucleic acid amplification techniques, led by real-time PCR, into
the clinical microbiology laboratory has transformed the laboratory detection of viruses and …

Acute respiratory infections (ARIs) are a common reason for seeking medical attention, and
the threat of pandemic influenza will likely add to these numbers. Using human viral …

The recognition of viral nucleic acids by host pattern recognition receptors (PRRs) is critical
for initiating innate immune responses against viral infections. These innate immune …

Airway epithelial cells (AECs) provide the first line of defense in the respiratory tract and are
the main target of respiratory viruses. Here, using oligonucleotide and protein arrays, we …

Respiratory viral infections, represent the leading cause of hospitalization in infants and
young children worldwide, and the second cause of infant mortality1. Of all respiratory …

Understanding how human neonates respond to infection remains incomplete. Here, a
system-level investigation of neonatal systemic responses to infection shows a surprisingly …

ISG12a is one of the most highly induced genes following treatment of cells with type I
interferons (IFNs). The encoded protein belongs to a family of poorly characterized, low …