Idiopathic intracranial hypertension: pathophysiology, diagnosis and management

MTM Wang, MT Bhatti, HV Danesh-Meyer - Journal of Clinical …, 2022 - Elsevier
Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure,
manifested by papilledema and radiological findings, in the absence of an identifiable …

Idiopathic intracranial hypertension: a step change in understanding the disease mechanisms

A Yiangou, SP Mollan, AJ Sinclair - Nature Reviews Neurology, 2023 - nature.com
The understanding of idiopathic intracranial hypertension (IIH) has evolved over the past few
years. Previously, IIH was considered a disease exclusively affecting the neuro-ophthalmic …

The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial

JL Mitchell, HS Lyons, JK Walker, A Yiangou, O Grech… - Brain, 2023 - academic.oup.com
Therapeutics to reduce intracranial pressure are an unmet need. Preclinical data have
demonstrated a novel strategy to lower intracranial pressure using glucagon-like peptide-1 …

The idiopathic intracranial hypertension prospective cohort study: evaluation of prognostic factors and outcomes

M Thaller, V Homer, Y Hyder, A Yiangou… - Journal of …, 2023 - Springer
Background There are limited longitudinal data evaluating outcomes in idiopathic
intracranial hypertension (IIH). We aimed to evaluate the long-term outcomes in a real-world …

Systemic and adipocyte transcriptional and metabolic dysregulation in idiopathic intracranial hypertension

CSJ Westgate, HF Botfield, Z Alimajstorovic… - JCI …, 2021 - pmc.ncbi.nlm.nih.gov
BACKGROUND Idiopathic intracranial hypertension (IIH) is a condition predominantly
affecting obese women of reproductive age. Recent evidence suggests that IIH is a disease …

An update on idiopathic intracranial hypertension in adults: a look at pathophysiology, diagnostic approach and management

S Toscano, S Lo Fermo, E Reggio, CG Chisari… - Journal of …, 2021 - Springer
Idiopathic intracranial hypertension is a neurological syndrome determined by a rise in
intracranial pressure without a detectable cause. Course and prognosis may be …

Headache attributed to idiopathic intracranial hypertension and persistent post‐idiopathic intracranial hypertension headache: a narrative review

SP Mollan, O Grech, AJ Sinclair - … The Journal of Head and Face …, 2021 - Wiley Online Library
Objective Headache is a near‐universal sequela of idiopathic intracranial hypertension (IIH).
The aim of this paper is to report current knowledge of headache in IIH and to identify …

Incidence, prevalence, and health care outcomes in idiopathic intracranial hypertension: a population study

L Miah, H Strafford, B Fonferko-Shadrach… - Neurology, 2021 - neurology.org
Objective To characterize trends in incidence, prevalence, and health care outcomes in the
idiopathic intracranial hypertension (IIH) population in Wales using routinely collected health …

Association of amount of weight lost after bariatric surgery with intracranial pressure in women with idiopathic intracranial hypertension

SP Mollan, JL Mitchell, A Yiangou, RS Ottridge… - Neurology, 2022 - neurology.org
Background and Objectives The idiopathic intracranial hypertension randomized controlled
weight trial (IIH: WT) established that weight loss through bariatric surgery significantly …