[HTML][HTML] Multiple nano-drug delivery systems for intervertebral disc degeneration: Current status and future perspectives
W Liu, Z Ma, Y Wang, J Yang - Bioactive Materials, 2023 - Elsevier
Low back pain (LBP) is a common disease that imposes a huge social and economic
burden on people. Intervertebral disc (IVD) degeneration (IVDD) is often considered to be …
burden on people. Intervertebral disc (IVD) degeneration (IVDD) is often considered to be …
Intervertebral disk degeneration and repair
Intervertebral disk (IVD) degeneration is a natural progression of the aging process.
Degenerative disk disease (DDD) is a pathologic condition associated with IVD that has …
Degenerative disk disease (DDD) is a pathologic condition associated with IVD that has …
[HTML][HTML] Epidural interventions in the management of chronic spinal pain: American Society of Interventional Pain Physicians (ASIPP) comprehensive evidence-based …
BACKGROUND: Chronic spinal pain is the most prevalent chronic disease with employment
of multiple modes of interventional techniques including epidural interventions. Multiple …
of multiple modes of interventional techniques including epidural interventions. Multiple …
Intervertebral disc diseases PART 2: a review of the current diagnostic and treatment strategies for intervertebral disc disease
PH Wu, HS Kim, IT Jang - International journal of molecular sciences, 2020 - mdpi.com
With an aging population, there is a proportional increase in the prevalence of intervertebral
disc diseases. Intervertebral disc diseases are the leading cause of lower back pain and …
disc diseases. Intervertebral disc diseases are the leading cause of lower back pain and …
Stem cells and exosomes: new therapies for intervertebral disc degeneration
Intervertebral disc degeneration (IVDD) occurs as a result of an imbalance of the anabolic
and catabolic processes in the intervertebral disc, leading to an alteration in the composition …
and catabolic processes in the intervertebral disc, leading to an alteration in the composition …
Biomaterials for intervertebral disc regeneration and repair
The intervertebral disc contributes to motion, weight bearing, and flexibility of the spine, but
is susceptible to damage and morphological changes that contribute to pathology with age …
is susceptible to damage and morphological changes that contribute to pathology with age …
[HTML][HTML] Disc in flames: roles of TNF-α and IL-1β in intervertebral disc degeneration
ZI Johnson, ZR Schoepflin, H Choi… - European cells & …, 2015 - ncbi.nlm.nih.gov
The intervertebral disc is an important mechanical structure that allows range of motion of
the spinal column. Degeneration of the intervertebral disc, incited by aging, traumatic insult …
the spinal column. Degeneration of the intervertebral disc, incited by aging, traumatic insult …
[HTML][HTML] TGF-β1-supplemented decellularized annulus fibrosus matrix hydrogels promote annulus fibrosus repair
Q Wei, D Liu, G Chu, Q Yu, Z Liu, J Li, Q Meng… - Bioactive Materials, 2023 - Elsevier
Annulus fibrosus (AF) repair remains a challenge because of its limited self-healing ability.
Endogenous repair strategies combining scaffolds and growth factors show great promise in …
Endogenous repair strategies combining scaffolds and growth factors show great promise in …
Materials for the spine: anatomy, problems, and solutions
Disc degeneration affects 12% to 35% of a given population, based on genetics, age,
gender, and other environmental factors, and usually occurs in the lumbar spine due to …
gender, and other environmental factors, and usually occurs in the lumbar spine due to …
Advancing the cellular and molecular therapy for intervertebral disc disease
The healthy intervertebral disc (IVD) fulfils the essential function of load absorption, while
maintaining multi-axial flexibility of the spine. The interrelated tissues of the IVD, the annulus …
maintaining multi-axial flexibility of the spine. The interrelated tissues of the IVD, the annulus …