Dopamine in Parkinson's disease

S Latif, M Jahangeer, DM Razia, M Ashiq, A Ghaffar… - Clinica chimica acta, 2021 - Elsevier
Parkinson's disease is a neurodegenerative disease caused by the death of neurons, ie,
cells critical to the production of dopamine, an important neurotransmitter in the brain. Here …

Current discoveries and future implications of eating disorders

B Feng, J Harms, E Chen, P Gao, P Xu… - International Journal of …, 2023 - mdpi.com
Eating disorders (EDs) are characterized by severe disturbances in eating behaviors and
can sometimes be fatal. Eating disorders are also associated with distressing thoughts and …

Perspectives on new strategies for the identification and development of insecticide targets

DR Swale - Pesticide biochemistry and physiology, 2019 - Elsevier
The discovery and development of new active ingredients to control arthropod populations
and circumvent the inevitable evolution of insecticide resistance has been of consistent …

Coevolutionary signals in metabotropic glutamate receptors capture residue contacts and long-range functional interactions

E Huh, MA Agosto, TG Wensel, O Lichtarge - Journal of Biological …, 2023 - ASBMB
Upon ligand binding to a G protein–coupled receptor, extracellular signals are transmitted
into a cell through sets of residue interactions that translate ligand binding into structural …

Two of a kind? Map** the psychopathological space between obesity with and without binge eating disorder

LM Sommer, G Halbeisen, Y Erim, G Paslakis - Nutrients, 2021 - mdpi.com
(1) Background: Obesity (OB) is a frequent co-morbidity in Binge Eating Disorder (BED),
suggesting that both conditions share phenotypical features along a spectrum of eating …

Exploring women's experiences of treatment for binge eating disorder: Methylphenidate vs. cognitive behavioural therapy

E Moghimi, C Davis, R Bonder, Y Knyahnytska… - Progress in Neuro …, 2022 - Elsevier
Objective The current qualitative study explored the personal experiences of a sample of
women with binge eating disorder (BED). The women were previously enrolled in a 12-week …

Co-occurring alcohol use disorder and obesity in US military veterans: Prevalence, risk factors, and clinical features

MM Carr, KL Serowik, PJ Na, MN Potenza… - Journal of Psychiatric …, 2022 - Elsevier
Obesity and alcohol use disorder (AUD) are two of the most prevalent and costly clinical
conditions among US military veterans, and these conditions often co-occur. However, little …

Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function

PJ Kearney, NC Bolden, E Kahuno, TL Conklin… - Journal of Biological …, 2023 - ASBMB
Extracellular dopamine (DA) levels are constrained by the presynaptic DA transporter (DAT),
a major psychostimulant target. Despite its necessity for DA neurotransmission, DAT …

Age-dependent effects of social isolation on mesolimbic dopamine release

MA McWain, RL Pace, PA Nalan, DB Lester - Experimental Brain Research, 2022 - Springer
In humans, social isolation is a known risk factor for disorders such as substance use
disorder and depression. In rodents, social isolation is a commonly used environmental …

Child eating behavior predicts body mass index after 1 year: results from the Swiss Preschooler's Health Study (SPLASHY)

Y Mihov, AH Meyer, TH Kakebeeke, K Stülb… - Frontiers in …, 2024 - frontiersin.org
Child obesity is a growing global issue. Preventing early development of overweight and
obesity requires identifying reliable risk factors for high body mass index (BMI) in children …