Soft‐tissue sarcoma in adults: an update on the current state of histiotype‐specific management in an era of personalized medicine

AC Gamboa, A Gronchi… - CA: a cancer journal for …, 2020 - Wiley Online Library
Soft‐tissue sarcomas (STS) are rare tumors that account for 1% of all adult malignancies,
with over 100 different histologic subtypes occurring predominately in the trunk, extremity …

Local cancer recurrence: the realities, challenges, and opportunities for new therapies

DA Mahvi, R Liu, MW Grinstaff… - CA: a cancer journal …, 2018 - Wiley Online Library
Locoregional recurrence negatively impacts both long‐term survival and quality of life for
several malignancies. For appropriate‐risk patients with an isolated, resectable, local …

Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label …

S Bonvalot, A Gronchi, C Le Péchoux… - The Lancet …, 2020 - thelancet.com
Background Unlike for extremity sarcomas, the efficacy of radiotherapy for retroperitoneal
sarcoma is not established. The aim of this study was to evaluate the impact of preoperative …

[HTML][HTML] Soft tissue and visceral sarcomas: ESMO–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

PG Casali, N Abecassis, S Bauer, R Biagini, S Bielack… - Annals of …, 2018 - Elsevier
Soft tissue sarcomas (STSs) gather over 80 histological entities, with even more molecular
subsets, characterised by a low to very low incidence in all populations. The majority of …

Management of primary retroperitoneal sarcoma (RPS) in the adult: an updated consensus approach from the Transatlantic Australasian RPS Working Group

CJ Swallow, DC Strauss, S Bonvalot… - Annals of surgical …, 2021 - Springer
Background Retroperitoneal soft tissue sarcomas comprise a heterogeneous group of rare
tumors of mesenchymal origin that include several well-defined histologic subtypes. In 2015 …

Preoperative radiotherapy in patients with primary retroperitoneal sarcoma: EORTC-62092 trial (STRASS) versus off-trial (STREXIT) results

D Callegaro, CP Raut, T Ajayi, D Strauss… - Annals of …, 2023 - journals.lww.com
Objective: The aim of the present study was to compare the effect of radiotherapy (RT) on
abdominal recurrence-free survival (ARFS) in patients with primary retroperitoneal sarcoma …

UK guidelines for the management of soft tissue sarcomas

AJ Hayes, IF Nixon, DC Strauss, BM Seddon… - British Journal of …, 2025 - nature.com
Soft tissue sarcomas (STS) are rare tumours arising in mesenchymal tissues and can occur
almost anywhere in the body. Their rarity, and the heterogeneity of subtype and location …

Cellular origin and clonal evolution of human dedifferentiated liposarcoma

N Gruel, C Quignot, L Lesage, S El Zein… - Nature …, 2024 - nature.com
Dedifferentiated liposarcoma (DDLPS) is the most frequent high-grade soft tissue sarcoma
subtype. It is characterized by a component of undifferentiated tumor cells coexisting with a …

Postoperative morbidity after radical resection of primary retroperitoneal sarcoma: a report from the transatlantic RPS working group

AJ MacNeill, A Gronchi, R Miceli, S Bonvalot… - Annals of …, 2018 - journals.lww.com
Objective: To investigate the safety of radical resection for retroperitoneal sarcoma (RPS).
Background: The surgical management of RPS frequently involves complex multivisceral …

Survival benefit of the surgical management of retroperitoneal sarcoma in a reference center: a nationwide study of the French Sarcoma Group from the NetSarc …

S Bonvalot, E Gaignard, E Stoeckle, P Meeus… - Annals of Surgical …, 2019 - Springer
Background Guidelines recommend that retroperitoneal sarcoma (RPS) be managed in a
reference sarcoma center (RSC), but the benefit remains to be demonstrated. This study …