Genetic load: genomic estimates and applications in non-model animals

G Bertorelle, F Raffini, M Bosse, C Bortoluzzi… - Nature Reviews …, 2022 - nature.com
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

Population genomics for wildlife conservation and management

PA Hohenlohe, WC Funk, OP Rajora - Molecular Ecology, 2021 - Wiley Online Library
Biodiversity is under threat worldwide. Over the past decade, the field of population
genomics has developed across nonmodel organisms, and the results of this research have …

A comparative genomics multitool for scientific discovery and conservation

Nature, 2020 - nature.com
Abstract The Zoonomia Project is investigating the genomics of shared and specialized traits
in eutherian mammals. Here we provide genome assemblies for 131 species, of which all …

Deleterious variation in natural populations and implications for conservation genetics

J Robinson, CC Kyriazis, SC Yuan… - Annual review of …, 2023 - annualreviews.org
Deleterious mutations decrease reproductive fitness and are ubiquitous in genomes. Given
that many organisms face ongoing threats of extinction, there is interest in elucidating the …

Genomic evidence for inbreeding depression and purging of deleterious genetic variation in Indian tigers

A Khan, K Patel, H Shukla… - Proceedings of the …, 2021 - National Acad Sciences
Increasing habitat fragmentation leads to wild populations becoming small, isolated, and
threatened by inbreeding depression. However, small populations may be able to purge …

Genomic signatures of extensive inbreeding in Isle Royale wolves, a population on the threshold of extinction

JA Robinson, J Räikkönen, LM Vucetich… - Science …, 2019 - science.org
The observation that small isolated populations often suffer reduced fitness from inbreeding
depression has guided conservation theory and practice for decades. However …

The intrepid urban coyote: a comparison of bold and exploratory behavior in coyotes from urban and rural environments

SW Breck, SA Poessel, P Mahoney, JK Young - Scientific reports, 2019 - nature.com
Coyotes (Canis latrans) are highly adaptable, medium-sized carnivores that now inhabit
nearly every large city in the United States and Canada. To help understand how coyotes …

[LIBRO][B] Molecular ecology

JR Freeland - 2020 - books.google.com
A fully updated guide to the increasingly prevalent use of molecular data in ecological
studies Molecular ecology is concerned with how molecular biology and population genetics …

Purging of strongly deleterious mutations explains long-term persistence and absence of inbreeding depression in island foxes

JA Robinson, C Brown, BY Kim, KE Lohmueller… - Current Biology, 2018 - cell.com
The recovery and persistence of rare and endangered species are often threatened by
genetic factors, such as the accumulation of deleterious mutations, loss of adaptive potential …

New developments in the field of genomic technologies and their relevance to conservation management

G Segelbacher, M Bosse, P Burger, P Galbusera… - Conservation …, 2022 - Springer
Recent technological advances in the field of genomics offer conservation managers and
practitioners new tools to explore for conservation applications. Many of these tools are well …