Background Duchenne muscular dystrophy (DMD) is a severe X-linked neuromuscular
childhood disorder that causes progressive muscle weakness and degeneration and results …

Imbalances in redox homeostasis can result in oxidative stress, which is implicated in
various pathological conditions including the fatal neuromuscular disease Duchenne …

Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disease. Recently
approved molecular/gene treatments do not solve the downstream inflammation-linked …

Skeletal muscle regeneration relies on the reciprocal interaction between many types of
cells. Regenerative capacity may be altered in different disorders. In our study, we …

Mdx mice with a spontaneous mutation in exon 23 of the Dmd gene represent the most
common model to investigate the pathophysiology of Duchenne muscular dystrophy (DMD) …

Hydrogen sulfide (H2S) has been known for years as a poisoning gas and until recently
evoked mostly negative associations. However, the discovery of its gasotransmitter functions …

Duchenne muscular dystrophy (DMD) represents one of the most devastating types of
muscular dystrophies which affect boys already at early childhood. Despite the fact that the …

In recent years, growing evidence has suggested a prominent role of oxidative stress in the
pathophysiology of several early-and adult-onset muscle disorders, although effective …

Skeletal muscle atrophy is a common muscle disease that is directly caused by an
imbalance in protein synthesis and degradation. At the histological level, it is mainly …

Duchenne muscular dystrophy (DMD) is an incurable disease caused by mutations in the X-
linked DMD gene that encodes a structural muscle protein, dystrophin. This, in turn, leads to …