Next-generation sequencing has made major strides in the past decade. Studies based on
large sequencing data sets are growing in number, and public archives for raw sequencing …

The great recent progress made in identifying the molecular parts lists of organisms
revealed the paucity of our understanding of what most of the parts do. In this review, we …

Protein structures can provide invaluable information, both for reasoning about biological
processes and for enabling interventions such as structure-based drug development or …

Protein-RNA interactions are fundamental to core biological processes, such as mRNA
splicing, localization, degradation, and translation. We developed a photoreactive …

A 3D atomistic model of a plant cellulose synthase (CESA) has remained elusive despite
over forty years of experimental effort. Here, we report a computationally predicted 3D …

Abstract dictyBase (http://dictybase. org), the model organism database for Dictyostelium
discoideum, includes the complete genome sequence and expression data for this …

Accurate structural information plays a crucial role in comprehending biological processes
and designing drugs. Indeed, the remarkable precision of the AlphaFold2 has facilitated …

Many scientific disciplines rely on computational methods for data analysis, model
generation, and prediction. Implementing these methods is often accomplished by …

Abstract Characterization of the role of oral microbiome in cancer therapy-induced oral
mucositis (CTOM) is critical in preventing the clinically deleterious effects on patients' health …

Accurate classification on protein structural is playing an important role in Bioinformatics. An
increase in evidence demonstrates that a variety of classification methods have been …