Originally, viruses were defined as miniscule infectious agents that passed through filters
that retain even the smallest cells. Subsequently, viruses were considered obligate …

Large DNA viruses of the phylum Nucleocytoviricota have recently emerged as important
members of ecosystems around the globe that challenge traditional views of viral …

Climate change is inducing wide-scale permafrost thaw in the Arctic and subarctic, triggering
concerns that long-dormant pathogens could reemerge from the thawing ground and initiate …

Recent discoveries of new large DNA viruses reveal high diversity in their morphologies,
genetic repertoires, and replication strategies. Here, we report the novel features of …

The nucleocytoplasmic large DNA viruses (NCLDV) of eukaryotes (proposed
order,“Megavirales”) include the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae …

Giant viruses with their gigantic genomes are among the most intriguing components of the
virosphere. How these viruses attained such giant genomes remains unclear, despite …

Viruses have long been viewed as entities possessing extremely limited metabolic
capacities. Over the last decade, however, this view has been challenged, as metabolic …

Giant viruses are complex members of the virosphere, exhibiting outstanding structural and
genomic features. Among these viruses, the pandoraviruses are some of the most intriguing …

Tupanviruses, members of the family Mimiviridae, infect phagocytic cells. Particle uncoating
begins inside the phagosome, with capsid opening via the stargate. The mechanism through …

The family of giant viruses is still expanding, and evidence of a translational machinery is
emerging in the virosphere. The Klosneuvirinae group of giant viruses was first …