[HTML][HTML] Therapeutic strategies of three-dimensional stem cell spheroids and organoids for tissue repair and regeneration

W Kim, Y Gwon, S Park, H Kim, J Kim - Bioactive Materials, 2023 - Elsevier
Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …

Soft bioelectronics based on nanomaterials

KW Cho, SH Sunwoo, YJ Hong, JH Koo… - Chemical …, 2021 - ACS Publications
Recent advances in nanostructured materials and unconventional device designs have
transformed the bioelectronics from a rigid and bulky form into a soft and ultrathin form and …

Hydrogels as functional components in artificial cell systems

ME Allen, JW Hindley, DK Baxani, O Ces… - Nature Reviews …, 2022 - nature.com
Recent years have seen substantial efforts aimed at constructing artificial cells from various
molecular components with the aim of mimicking the processes, behaviours and …

[HTML][HTML] Recent advances in defined hydrogels in organoid research

Z Gan, X Qin, H Liu, J Liu, J Qin - Bioactive materials, 2023 - Elsevier
Organoids are in vitro model systems that mimic the complexity of organs with multicellular
structures and functions, which provide great potential for biomedical and tissue …

Flexible, transparent, and antibacterial ionogels toward highly sensitive strain and temperature sensors

N Jiang, X Chang, D Hu, L Chen, Y Wang… - Chemical Engineering …, 2021 - Elsevier
Skin-like sensor has recently emerged for its promising applications in human motion
monitoring and healthcare. However, it is challenging to develop flexible skin-like sensors …

Vascularized organoids on a chip: strategies for engineering organoids with functional vasculature

S Zhang, Z Wan, RD Kamm - Lab on a Chip, 2021 - pubs.rsc.org
Human organoids, self-organized and differentiated from homogenous pluripotent stem cells
(PSC), replicate the key structural and functional characteristics of their in vivo counterparts …

Beyond polydimethylsiloxane: alternative materials for fabrication of organ-on-a-chip devices and microphysiological systems

SB Campbell, Q Wu, J Yazbeck, C Liu… - ACS biomaterials …, 2020 - ACS Publications
Polydimethylsiloxane (PDMS) is the predominant material used for organ-on-a-chip devices
and microphysiological systems (MPSs) due to its ease-of-use, elasticity, optical …

[HTML][HTML] An overview of in vitro 3D models of the blood-brain barrier as a tool to predict the in vivo permeability of nanomedicines

A Pérez-López, AI Torres-Suárez… - Advanced Drug Delivery …, 2023 - Elsevier
The blood–brain barrier (BBB) prevents efficient drug delivery to the central nervous system.
As a result, brain diseases remain one of the greatest unmet medical needs. Understanding …

Biomaterial-assisted biotherapy: A brief review of biomaterials used in drug delivery, vaccine development, gene therapy, and stem cell therapy

X Han, A Alu, H Liu, Y Shi, X Wei, L Cai, Y Wei - Bioactive materials, 2022 - Elsevier
Biotherapy has recently become a hotspot research topic with encouraging prospects in
various fields due to a wide range of treatments applications, as demonstrated in preclinical …

[HTML][HTML] Advances in hydrogel-based vascularized tissues for tissue repair and drug screening

Y Wang, RK Kankala, C Ou, A Chen, Z Yang - Bioactive materials, 2022 - Elsevier
The construction of biomimetic vasculatures within the artificial tissue models or organs is
highly required for conveying nutrients, oxygen, and waste products, for improving the …