Key determinants for the development of an allergic response to an otherwise 'harmless'
food protein involve different factors like the predisposition of the individual, the timing, the …

Actin is a key structural protein that makes up the cytoskeleton of cells, and plays a role in
functions such as division, migration, and vesicle trafficking. It comprises six different cell …

Protein N-terminal acetylation (Nt-acetylation) is an important mediator of protein function,
stability, sorting, and localization. Although the responsible enzymes are thought to be fairly …

Eukaryotic cells generate a diversity of actin filament networks in a common cytoplasm to
optimally perform functions such as cell motility, cell adhesion, endocytosis and cytokinesis …

The actin cytoskeleton, which regulates cell polarity, adhesion, and migration, can influence
cancer progression, including initial acquisition of malignant properties by normal cells …

Microtubule-disturbing drugs inhibit lysosomal trafficking and induce lysosomal membrane
permeabilization followed by cathepsin-dependent cell death. To identify specific trafficking …

Tropomyosin is the archetypal-coiled coil, yet studies of its structure and function have
proven it to be a dynamic regulator of actin filament function in muscle and non-muscle cells …

Dengue, an arboviral disease is a global threat to public health as the number of Dengue
cases increases through the decades and this trend is predicted to continue. Non …

The interactions of cytoskeletal actin filaments with myosin family motors are essential for the
integrity and function of eukaryotic cells. They support a wide range of force-dependent …

Alternative splicing generates specialized protein isoforms that allow the heart to adapt
during development and disease. The recent discovery that mutations in the splicing factor …