Polymerization of ethylene oxide, propylene oxide, and other alkylene oxides: synthesis, novel polymer architectures, and bioconjugation

J Herzberger, K Niederer, H Pohlit, J Seiwert… - Chemical …, 2016 - ACS Publications
The review summarizes current trends and developments in the polymerization of alkylene
oxides in the last two decades since 1995, with a particular focus on the most important …

Aqueous two-phase system (ATPS): an overview and advances in its applications

M Iqbal, Y Tao, S **e, Y Zhu, D Chen, X Wang… - Biological procedures …, 2016 - Springer
Aqueous two-phase system (ATPS) is a liquid-liquid fractionation technique and has gained
an interest because of great potential for the extraction, separation, purification and …

Recent advances in large-scale production of monoclonal antibodies and related proteins

AA Shukla, J Thömmes - Trends in biotechnology, 2010 - cell.com
The rapid development of high-yielding and robust manufacturing processes for monoclonal
antibodies is an area of significant focus in the biopharmaceutical landscape. Advances in …

Trends in upstream and downstream process development for antibody manufacturing

P Gronemeyer, R Ditz, J Strube - Bioengineering, 2014 - mdpi.com
A steady increase of product titers and the corresponding change in impurity composition
represent a challenge for development and optimization of antibody production processes …

Evolving trends in mAb production processes

AA Shukla, LS Wolfe, SS Mostafa… - Bioengineering & …, 2017 - Wiley Online Library
Monoclonal antibodies (mAbs) have established themselves as the leading
biopharmaceutical therapeutic modality. The establishment of robust manufacturing …

Biopharmaceuticals from microorganisms: from production to purification

AF Jozala, DC Geraldes, LL Tundisi… - brazilian journal of …, 2016 - SciELO Brasil
The use of biopharmaceuticals dates from the 19th century and within 5-10 years, up to 50%
of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical …

[HTML][HTML] Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications

B Wiltschi, T Cernava, A Dennig, MG Casas… - Biotechnology …, 2020 - Elsevier
Competitive sustainable production in industry demands new and better biocatalysts,
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …

Bromelain: an overview of industrial application and purification strategies

ZIM Arshad, A Amid, F Yusof, I Jaswir, K Ahmad… - Applied microbiology …, 2014 - Springer
This review highlights the use of bromelain in various applications with up-to-date literature
on the purification of bromelain from pineapple fruit and waste such as peel, core, crown …

Partitioning in aqueous two-phase systems: fundamentals, applications and trends

AL Grilo, M Raquel Aires-Barros… - Separation & Purification …, 2016 - Taylor & Francis
Over the last years, aqueous two-phase systems (ATPS) regained an increasing interest due
to their potential in the downstream processing of biomolecules. After many years with only a …

[PDF][PDF] Aqueous two phase systems for the recovery of biomolecules–a review

S Raja, VR Murty, V Thivaharan, V Rajasekar… - Sci Technol, 2011 - academia.edu
Aqueous two phase system (ATPS) is a liquid–liquid extraction method which employs two
aqueous phases having applications in the field of biotechnology for the separation and …