Bioengineered nanogels for cancer immunotherapy

X Ma, SJ Li, Y Liu, T Zhang, P Xue, Y Kang… - Chemical Society …, 2022 - pubs.rsc.org
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …

Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021 - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …

Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications

YH Chung, H Cai, NF Steinmetz - Advanced Drug Delivery Reviews, 2020 - Elsevier
Viral nanoparticles (VNPs) encompass a diverse array of naturally occurring nanomaterials
derived from plant viruses, bacteriophages, and mammalian viruses. The application and …

Injectable immunotherapeutic hydrogel containing RNA-loaded lipid nanoparticles reshapes tumor microenvironment for pancreatic cancer therapy

C Gao, K Cheng, Y Li, R Gong, X Zhao, G Nie… - Nano …, 2022 - ACS Publications
Pancreatic cancer immunotherapy is becoming a promising strategy for improving the
survival rate of postsurgical patients. However, the low response rate to immunotherapy …

Multifunctional nanoparticle-loaded Injectable Alginate Hydrogels with Deep Tumor Penetration for enhanced chemo-immunotherapy of Cancer

X Yang, C Huang, H Wang, K Yang, M Huang… - ACS …, 2024 - ACS Publications
Chemo-immunotherapy has become a promising strategy for cancer treatment. However,
the inability of the drugs to penetrate deeply into the tumor and form potent tumor vaccines in …

Rational design of a minimalist nanoplatform to maximize immunotherapeutic efficacy: Four birds with one stone

S Zhou, Q Shang, N Wang, Q Li, A Song… - Journal of Controlled …, 2020 - Elsevier
Chemotherapy sometimes can cause potential tumor-specific T-cell-mediated immune
response via stimulating immunogenic cell death (ICD). However, such immune response is …

Photothermal “nano-dot” reactivate “immune-hot” for tumor treatment via reprogramming cancer cells metabolism

Y Lu, Y Wang, W Liu, H Ma, B Yang, K Shao, S Long… - Biomaterials, 2023 - Elsevier
Cancer immunotherapy, despite its enormous application prospect, is trapped in the
abnormal lactic acid metabolism of tumor cells that usually causes an immunosuppressive …

[HTML][HTML] Nanogel: A versatile nano-delivery system for biomedical applications

Y Yin, B Hu, X Yuan, L Cai, H Gao, Q Yang - Pharmaceutics, 2020 - mdpi.com
Nanogel-based nanoplatforms have become a tremendously promising system of drug
delivery. Nanogels constructed by chemical crosslinking or physical self-assembly exhibit …

Photothermal-chemotherapy enhancing tumor immunotherapy by multifunctional metal–organic framework based drug delivery system

W Ni, J Wu, H Fang, Y Feng, Y Hu, L Lin, J Chen… - Nano Letters, 2021 - ACS Publications
Immunotherapy holds great promise for patients undergoing tumor treatment. However, the
clinical effect of immunotherapy is limited because of tumor immunogenicity and its …

Multifunctional nanoparticle loaded injectable thermoresponsive hydrogel as NIR controlled release platform for local photothermal immunotherapy to prevent breast …

YP Jia, K Shi, F Yang, JF Liao, RX Han… - Advanced Functional …, 2020 - Wiley Online Library
For breast cancer patients who have undergone breast‐conserving surgery, effective
treatments to prevent local recurrences and metastases is very essential. Here, a local …