Antimicrobial resistance represents an enormous global health crisis and one of the most
serious threats humans face today. Some bacterial strains have acquired resistance to …

Traditional organic antimicrobials mainly act on specific biochemical processes such as
replication, transcription and translation. However, the emergence and wide spread of …

There is a dire need for new antimicrobial compounds to combat the growing threat of
widespread antibiotic resistance. With a currently very scarce drug pipeline, consisting …

Cyclic (alkyl)-and (aryl)-(amino) carbenes (CAACs and CAArCs) are stronger σ-donors and
π-acceptors than imidazol-2-ylidenes and imidazolidin-2-ylidenes, the well-known N …

Nanoscience enables researchers to develop new and cost-effective nanomaterials for
energy, healthcare, and medical applications. Silver nanoparticles (Ag NPs) are currently …

Antimicrobial resistance (AMR) is one of the greatest global health challenges of modern
times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of …

Although the coordination chemistry of N-heterocyclic carbenes (NHCs) with transition
metals has been explored for half a century, only in the past ten years has the chemistry of …

With the widespread rise of antimicrobial resistance, most traditional sources for new drug
compounds have been explored intensively for new classes of antibiotics. Meanwhile, metal …

To date, there are no antimicrobial agents available in the market that have absolute control
over the growing threat of bacterial strains. The increase in the production capacity of …

Silver has been used for numerous medical conditions for centuries, however, most of the
current clinical silver agents all have their own disadvantages limiting the clinical …