Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA

P Wu, Y Mo, M Peng, T Tang, Y Zhong, X Deng… - Molecular cancer, 2020‏ - Springer
Non-coding RNAs do not encode proteins and regulate various oncological processes. They
are also important potential cancer diagnostic and prognostic biomarkers. Bioinformatics …

Epigenetics: Roles and therapeutic implications of non-coding RNA modifications in human cancers

D Rong, G Sun, F Wu, Y Cheng, G Sun, W Jiang… - … therapy Nucleic acids, 2021‏ - cell.com
As next-generation sequencing (NGS) is lea** forward, more than 160 covalent RNA
modification processes have been reported, and they are widely present in every organism …

m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome

Y Tang, K Chen, B Song, J Ma, X Wu, Q Xu… - Nucleic acids …, 2021‏ - academic.oup.com
Abstract N 6-Methyladenosine (m6A) is the most prevalent RNA modification on mRNAs and
lncRNAs. It plays a pivotal role during various biological processes and disease …

m7GHub: deciphering the location, regulation and pathogenesis of internal mRNA N7-methylguanosine (m7G) sites in human

B Song, Y Tang, K Chen, Z Wei, R Rong, Z Lu… - …, 2020‏ - academic.oup.com
Motivation Recent progress in N7-methylguanosine (m7G) RNA methylation studies has
focused on its internal (rather than capped) presence within mRNAs. Tens of thousands of …

RMDisease: a database of genetic variants that affect RNA modifications, with implications for epitranscriptome pathogenesis

K Chen, B Song, Y Tang, Z Wei, Q Xu, J Su… - Nucleic acids …, 2021‏ - academic.oup.com
Deciphering the biological impacts of millions of single nucleotide variants remains a major
challenge. Recent studies suggest that RNA modifications play versatile roles in essential …

Advances in the profiling of N6-methyladenosine (m6A) modifications

H Zheng, X Zhang, N Sui - Biotechnology Advances, 2020‏ - Elsevier
Over 160 RNA modifications have been identified, including N 7-methylguanine (m 7 G), N 6-
methyladenosine (m 6 A), and 5-methylcytosine (m 5 C). These modifications play key roles …

RF-PseU: a random forest predictor for RNA pseudouridine sites

Z Lv, J Zhang, H Ding, Q Zou - Frontiers in Bioengineering and …, 2020‏ - frontiersin.org
One of the ubiquitous chemical modifications in RNA, pseudouridine modification is crucial
for various cellular biological and physiological processes. To gain more insight into the …

Predicting RNA 5‐Methylcytosine Sites by Using Essential Sequence Features and Distributions

L Chen, ZD Li, SQ Zhang, YH Zhang… - BioMed Research …, 2022‏ - Wiley Online Library
Methylation is one of the most common and considerable modifications in biological systems
mediated by multiple enzymes. Recent studies have shown that methylation has been …

Circular RNAs with protein-coding ability in oncogenesis

J Cheng, G Li, W Wang, DB Stovall, G Sui… - Biochimica et Biophysica …, 2023‏ - Elsevier
As ubiquitously expressed transcripts in eukaryotes, circular RNAs (circRNAs) are covalently
closed and lack a 5′-cap and 3′-polyadenylation (poly (A)) tail. Initially, circRNAs were …

[HTML][HTML] Bioinformatics approaches for deciphering the epitranscriptome: recent progress and emerging topics

L Liu, B Song, J Ma, Y Song, SY Zhang, Y Tang… - Computational and …, 2020‏ - Elsevier
Post-transcriptional RNA modification occurs on all types of RNA and plays a vital role in
regulating every aspect of RNA function. Thanks to the development of high-throughput …