Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Human amniotic epithelial cells (hAECs) derived from placental tissues have gained
considerable attention in the field of regenerative medicine. hAECs possess embryonic stem …

Periodontitis is a worldwide chronic inflammatory disease, where surgical treatment still
shows an uncertain prognosis. To break through the dilemma of periodontal treatment, we …

Sensing the mechanical properties of the substrates or the matrix by the cells and the
tissues, the subsequent downstream responses at the cellular, nuclear and epigenetic levels …

Adult tendon tissue demonstrates a limited regenerative capacity, and the natural repair
process leaves fibrotic scar tissue with inferior mechanical properties. Surgical treatment is …

Inflammation plays a central role in wound healing following injury or disease and is
mediated by a precise cascade of cellular and molecular events. Unresolved inflammatory …

Tendon injuries often result in significant pain and disability and impose severe clinical and
financial burdens on our society. Despite considerable achievements in the field of …

Musculoskeletal disorders are common in clinical practice. Repairing critical-sized defects in
musculoskeletal systems remains a challenge for researchers and surgeons, requiring the …

With an increase in life expectancy and the popularity of high-intensity exercise, the
frequency of tendon and ligament injuries has also increased. Owing to the specificity of its …