Innate immune system activation, inflammation and corneal wound healing
N Fortingo, S Melnyk, SH Sutton, MA Watsky… - International journal of …, 2022 - mdpi.com
Corneal wounds resulting from injury, surgeries, or other intrusions not only cause pain, but
also can predispose an individual to infection. While some inflammation may be beneficial to …
also can predispose an individual to infection. While some inflammation may be beneficial to …
Updated perspectives on keratinocytes and psoriasis: keratinocytes are more than innocent bystanders
LI Ortiz-Lopez, V Choudhary… - Psoriasis: Targets and …, 2022 - Taylor & Francis
Psoriasis is a complex disease triggered by genetic, immunologic, and environmental
stimuli. Many genes have been linked to psoriasis, like the psoriasis susceptibility genes …
stimuli. Many genes have been linked to psoriasis, like the psoriasis susceptibility genes …
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs
The broad clinical application of mRNA therapeutics has been hampered by a lack of
delivery vehicles that induce protein expression in extrahepatic organs and tissues …
delivery vehicles that induce protein expression in extrahepatic organs and tissues …
Gasdermin D-mediated keratinocyte pyroptosis as a key step in psoriasis pathogenesis
N Lian, Y Chen, S Chen, Y Zhang, H Chen… - Cell Death & …, 2023 - nature.com
Gasdermin D (GSDMD)-mediated pyroptosis has a significant pro-inflammation
characteristic due to dramatic secretion of pro-inflammatory substances. However, its role …
characteristic due to dramatic secretion of pro-inflammatory substances. However, its role …
[HTML][HTML] DAMPs in immunosenescence and cancer
Damage-associated molecular patterns (DAMPs) are endogenous molecules released by
cells in response to injury or stress, recognized by host pattern recognition receptors that …
cells in response to injury or stress, recognized by host pattern recognition receptors that …
Aquaporin-3 in the epidermis: more than skin deep
The skin is essential for terrestrial life. It is responsible for regulating water permeability and
functions as a mechanical barrier that protects against environmental insults such as …
functions as a mechanical barrier that protects against environmental insults such as …
Fat of the gut: epithelial phospholipids in inflammatory bowel diseases
LV Boldyreva, MV Morozova, SS Saydakova… - International journal of …, 2021 - mdpi.com
Inflammatory bowel diseases (IBD) comprise a distinct set of clinical symptoms resulting
from chronic inflammation within the gastrointestinal (GI) tract. Despite the significant …
from chronic inflammation within the gastrointestinal (GI) tract. Despite the significant …
Long-term chronic food-derived arsenic exposure induce the urinary system metabolic dysfunction in mice
The consumption of rice contaminated with arsenic on a long-term basis has emerged as a
pressing public health issue of global significance. Arsenic-induced urinary injury …
pressing public health issue of global significance. Arsenic-induced urinary injury …
High-confidence structural annotation of substances via multi-layer molecular network reveals the system-wide constituent alternations in milk interfered with …
Z Fan, W Jia - Journal of Hazardous Materials, 2024 - Elsevier
The spectral database-based mass spectrometry (MS) matching strategy is versatile for
structural annotating in ingredient fluctuation profiling mediated by external interferences …
structural annotating in ingredient fluctuation profiling mediated by external interferences …
[HTML][HTML] Luteolin attenuates imiquimod–induced psoriasis-like skin lesions in BALB/c mice via suppression of inflammation response
W Zhou, M Hu, X Zang, Q Liu, J Du, J Hu… - Biomedicine & …, 2020 - Elsevier
Psoriasis is considered as a common chronic immune-mediated skin disorder characterized
by abnormal keratinocyte proliferation. Luteolin, an anti-inflammatory natural flavonoid with …
by abnormal keratinocyte proliferation. Luteolin, an anti-inflammatory natural flavonoid with …