Achalasia: a systematic review

JE Pandolfino, AJ Gawron - Jama, 2015 - jamanetwork.com
Importance Achalasia significantly affects patients' quality of life and can be difficult to
diagnose and treat. Objective To review the diagnosis and management of achalasia, with a …

Achalasia

GE Boeckxstaens, G Zaninotto, JE Richter - The Lancet, 2014 - thelancet.com
Achalasia is a rare motility disorder of the oesophagus characterised by loss of enteric
neurons leading to absence of peristalsis and impaired relaxation of the lower oesophageal …

ASGE guideline on the management of achalasia

MA Khashab, MF Vela, N Thosani, D Agrawal… - Gastrointestinal …, 2020 - Elsevier
Achalasia is a primary esophageal motor disorder of unknown etiology characterized by
degeneration of the myenteric plexus, which results in impaired relaxation of the …

Treatment of achalasia: botulinum toxin injection vs. pneumatic balloon dilation. A prospective study with long-term follow-up

HD Allescher, M Storr, M Seige… - …, 2001 - thieme-connect.com
Results: There were significant improvements in the global symptom scores of all patients
treated, in both the BTX injection group (before 8.2±1.3, after 3.0±1.6) and the dilation group …

GERD after per-oral endoscopic myotomy as compared with Heller's myotomy with fundoplication: a systematic review with meta-analysis

A Repici, L Fuccio, R Maselli, F Mazza… - Gastrointestinal …, 2018 - Elsevier
Background and Aims Per-oral endoscopic myotomy (POEM) represents a less invasive
alternative to conventional laparoscopic Heller's myotomy (LHM) for patients with achalasia …

ACG clinical guideline: diagnosis and management of achalasia

MF Vaezi, JE Pandolfino, MF Vela - Official journal of the …, 2013 - journals.lww.com
Achalasia is a primary motor disorder of the esophagus characterized by insufficient lower
esophageal sphincter relaxation and loss of esophageal peristalsis. This results in patients' …

Achalasia: a new clinically relevant classification by high-resolution manometry

JE Pandolfino, MA Kwiatek, T Nealis, W Bulsiewicz… - Gastroenterology, 2008 - Elsevier
BACKGROUND & AIMS: Although the diagnosis of achalasia hinges on demonstrating
impaired esophagogastric junction (EGJ) relaxation and aperistalsis, 3 distinct patterns of …

Endoscopic and surgical treatments for achalasia: a systematic review and meta-analysis

GM Campos, E Vittinghoff, C Rabl, M Takata… - Annals of …, 2009 - journals.lww.com
Background: Although rare, esophageal achalasia is the best described primary esophageal
motility disorder. Commonly used treatments are endoscopic botulin toxin injection (EBTI) …

Achalasia: incidence, prevalence and survival. A population‐based study

DC Sadowski, F Ackah, B Jiang… - Neurogastroenterology …, 2010 - Wiley Online Library
Background Studies of achalasia epidemiology are important as they often yield new
insights into disease etiology. In this study, our objective was to carry out the first North …

Botulinum toxin A for the treatment of delayed gastric emptying

FK Friedenberg, A Palit, HP Parkman… - Official journal of the …, 2008 - journals.lww.com
BACKGROUND Observational data suggest that intrapyloric injection of botulinum toxin A
(BoTN/A) reduces symptoms and accelerates gastric emptying in idiopathic and diabetic …