Clinical guidelines in the use of fibre supplementation for patients with IBS provide one-size-
fits-all advice, which has limited value. This narrative review addresses data and concepts …

Background & Aims Probiotics can reduce symptoms of irritable bowel syndrome (IBS), but
little is known about their effects on psychiatric comorbidities. We performed a prospective …

Background Probiotics are often taken by individuals with irritable bowel syndrome (IBS).
Which products are effective is unclear, despite an increasing research base. This project …

It is commonly believed that blinding to treatment assignment is necessary for placebos to
have an effect. However, placebos administered without concealment (ie, open-label …

BACKGROUND & AIMS:: Linaclotide, a minimally absorbed, 14-amino acid peptide agonist
of guanylate cyclase-C, has shown benefit in a proof-of-concept study for the treatment of …

AIM To determine the effects of Lactobacillus acidophilus NCFM on irritable bowel syndrome
(IBS) symptoms and quality of life (QoL). METHODS In this randomized triple-blind trial, adult …

BACKGROUND Probiotics have shown promise in alleviating symptoms of diarrhea-
predominant irritable bowel syndrome (IBS-D); however, the certainty of evidence is low …

We conducted a meta-analysis exploring the effect of a low fermentable oligo-, di-,
monosaccharides, and polyols diet (LFD) on the overall symptoms, quality of life, and stool …

Introduction. Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that
affects the quality of life of numerous people worldwide. Gap statement. The therapeutic role …

Objective. Meta-analyses have indicated effect of probiotics on irritable bowel syndrome
(IBS). However, few long-term trials have been conducted and uncertainty remains as to …