Research progress in protein posttranslational modification site prediction

W He, L Wei, Q Zou - Briefings in functional genomics, 2019 - academic.oup.com
Posttranslational modifications (PTMs) play an important role in regulating protein folding,
activity and function and are involved in almost all cellular processes. Identification of PTMs …

Prediction of citrullination sites by incorporating k-spaced amino acid pairs into Chou's general pseudo amino acid composition

Z Ju, SY Wang - Gene, 2018 - Elsevier
As one of the most important and common protein post-translational modifications,
citrullination plays a key role in regulating various biological processes and is associated …

hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties

Z Chen, Y Zhou, J Song, Z Zhang - … et Biophysica Acta (BBA)-Proteins and …, 2013 - Elsevier
As one of the most common post-translational modifications, ubiquitination regulates the
quantity and function of a variety of proteins. Experimental and clinical investigations have …

UbiSitePred: A novel method for improving the accuracy of ubiquitination sites prediction by using LASSO to select the optimal Chou's pseudo components

X Cui, Z Yu, B Yu, M Wang, B Tian, Q Ma - Chemometrics and Intelligent …, 2019 - Elsevier
Ubiquitination is an essential process in protein post-translational modification, which plays
a crucial role in cell life activities, such as proteasomal degradation, transcriptional …

pCysMod: prediction of multiple cysteine modifications based on deep learning framework

S Li, K Yu, G Wu, Q Zhang, P Wang, J Zheng… - Frontiers in Cell and …, 2021 - frontiersin.org
Thiol groups on cysteines can undergo multiple post-translational modifications (PTMs),
acting as a molecular switch to maintain redox homeostasis and regulating a series of cell …

DeepTL-Ubi: a novel deep transfer learning method for effectively predicting ubiquitination sites of multiple species

Y Liu, A Li, XM Zhao, M Wang - Methods, 2021 - Elsevier
Ubiquitination is one of the most important post-translational modifications which involves in
many biological processes. Because mass spectrometry-based ubiquitination site …

Computational Identification of Protein Pupylation Sites by Using Profile-Based Composition of k-Spaced Amino Acid Pairs

MM Hasan, Y Zhou, X Lu, J Li, J Song, Z Zhang - PloS one, 2015 - journals.plos.org
Prokaryotic proteins are regulated by pupylation, a type of post-translational modification
that contributes to cellular function in bacterial organisms. In pupylation process, the …

[HTML][HTML] PTM-ssMP: a web server for predicting different types of post-translational modification sites using novel site-specific modification profile

Y Liu, M Wang, J **, F Luo, A Li - International journal of biological …, 2018 - ncbi.nlm.nih.gov
Protein post-translational modifications (PTMs) are chemical modifications of a protein after
its translation. Owing to its play an important role in deep understanding of various biological …

A cascaded QSAR model for efficient prediction of overall power conversion efficiency of all‐organic dye‐sensitized solar cells

H Li, Z Zhong, L Li, R Gao, J Cui, T Gao… - Journal of …, 2015 - Wiley Online Library
A cascaded model is proposed to establish the quantitative structure–activity relationship
(QSAR) between the overall power conversion efficiency (PCE) and quantum chemical …

Crysalis: an integrated server for computational analysis and design of protein crystallization

H Wang, L Feng, Z Zhang, GI Webb, D Lin, J Song - Scientific reports, 2016 - nature.com
The failure of multi-step experimental procedures to yield diffraction-quality crystals is a
major bottleneck in protein structure determination. Accordingly, several bioinformatics …