The accuracy and scalability of multiple sequence alignment (MSA) of DNAs and proteins
have long been and are still important issues in bioinformatics. To rapidly construct a …

Over the past few decades, the number of available structural bioinformatics pipelines,
libraries, plugins, web resources and software has increased exponentially and become …

Background The quality of multiple sequence alignments plays an important role in the
accuracy of phylogenetic inference. It has been shown that removing ambiguously aligned …

Multiple alignment of DNA sequences is an important step in various molecular biological
analyses. As a large amount of sequence data is becoming available through genome and …

Although multiple sequence alignments (MSAs) are essential for a wide range of
applications from structure modeling to prediction of functional sites, construction of accurate …

Motivation: A tool that simultaneously aligns multiple protein sequences, automatically
utilizes information about protein domains, and has a good compromise between speed and …

Genome sequence analysis has enabled significant advancements in medical and scientific
areas such as personalized medicine, outbreak tracing, and the understanding of evolution …

Blockchains have been booming in recent years. As a decentralized system architecture,
smart contracts give blockchains a user-defined logic. A smart contract is an executable …

Many disciplines, from human genetics and oncology to plant breeding, microbiology and
virology, commonly face the challenge of analyzing rapidly increasing numbers of genomes …

The functions of most long non-coding RNAs (lncRNAs) are unknown. In contrast to proteins,
lncRNAs with similar functions often lack linear sequence homology; thus, the identification …