Key determinants of success in fecal microbiota transplantation: From microbiome to clinic

S Porcari, N Benech, M Valles-Colomer, N Segata… - Cell host & …, 2023 - cell.com
Fecal microbiota transplantation (FMT) has achieved satisfactory results in preventing the
recurrence of Clostridioides difficile infection, but these positive outcomes have only been …

Treatment of inflammatory bowel disease: a comprehensive review

Z Cai, S Wang, J Li - Frontiers in medicine, 2021 - frontiersin.org
Inflammatory bowel disease (IBD), as a global disease, has attracted much research
interest. Constant research has led to a better understanding of the disease condition and …

Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

B Routy, JG Lenehan, WH Miller Jr, R Jamal… - Nature medicine, 2023 - nature.com
Fecal microbiota transplantation (FMT) represents a potential strategy to overcome
resistance to immune checkpoint inhibitors in patients with refractory melanoma; however …

[HTML][HTML] European Society of Clinical Microbiology and Infectious Diseases: 2021 update on the treatment guidance document for Clostridioides difficile infection in …

J Van Prehn, E Reigadas, EH Vogelzang… - Clinical Microbiology …, 2021 - Elsevier
Abstract Scope In 2009, the European Society of Clinical Microbiology and Infectious
Diseases (ESCMID) published the first treatment guidance document for Clostridioides …

Fecal microbial transplantation and fiber supplementation in patients with severe obesity and metabolic syndrome: a randomized double-blind, placebo-controlled …

V Mocanu, Z Zhang, EC Deehan, DH Kao, N Hotte… - Nature medicine, 2021 - nature.com
Fecal microbial transplantation (FMT) from lean donors to patients with obesity has been
associated with metabolic benefits, yet results so far have been inconsistent. In this study …

The microbiome, cancer, and cancer therapy

BA Helmink, MAW Khan, A Hermann… - Nature medicine, 2019 - nature.com
With the advent of next-generation sequencing, we have an unprecedented ability to study
tumor and host genomes as well as those of the vast array of microorganisms that exist …

Fecal microbiota transplantation promotes reduction of antimicrobial resistance by strain replacement

MH Woodworth, RE Conrad, M Haldopoulos… - Science translational …, 2023 - science.org
Multidrug-resistant organism (MDRO) colonization is a fundamental challenge in
antimicrobial resistance. Limited studies have shown that fecal microbiota transplantation …

Targeted delivery of the probiotic Saccharomyces boulardii to the extracellular matrix enhances gut residence time and recovery in murine colitis

MK Heavey, A Hazelton, Y Wang, M Garner… - Nature …, 2024 - nature.com
Probiotic and engineered microbe-based therapeutics are an emerging class of
pharmaceutical agents. They represent a promising strategy for treating various chronic and …

Chemically and biologically engineered bacteria‐based delivery systems for emerging diagnosis and advanced therapy

Z Li, Y Wang, J Liu, P Rawding, J Bu… - Advanced …, 2021 - Wiley Online Library
Bacteria are one of the main groups of organisms, which dynamically and closely participate
in human health and disease development. With the integration of chemical biotechnology …

Transplantation of gut microbiota derived from Alzheimer's disease mouse model impairs memory function and neurogenesis in C57BL/6 mice

N Kim, SH Jeon, IG Ju, MS Gee, J Do, MS Oh… - Brain, Behavior, and …, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease that causes memory and cognitive
decline. Although many studies have attempted to clarify the causes of AD occurrence, it is …