Plant unsaturated fatty acids: biosynthesis and regulation

M He, CX Qin, X Wang, NZ Ding - Frontiers in Plant Science, 2020 - frontiersin.org
In most plants, major unsaturated fatty acids (UFAs) are three C18 species, namely, oleic
(18: 1), linoleic (18: 2), and α-linolenic (18: 3) acids. These simple compounds play multiple …

Regulatory mechanisms of lipid biosynthesis in microalgae

H Chen, Q Wang - Biological Reviews, 2021 - Wiley Online Library
Microalgal lipids are highly promising feedstocks for biofuel production. Microalgal lipids,
especially triacylglycerol, and practical applications of these compounds have received …

Carbon/nitrogen homeostasis control in cyanobacteria

K Forchhammer, KA Selim - FEMS microbiology reviews, 2020 - academic.oup.com
ABSTRACT Carbon/nitrogen (C/N) balance sensing is a key requirement for the
maintenance of cellular homeostasis. Therefore, cyanobacteria have evolved a …

Recent progress in the synthesis of advanced biofuel and bioproducts

BF Pfleger, R Takors - Current Opinion in Biotechnology, 2023 - Elsevier
Highlights●Why biofuels and bioproducts remain critical to society●What molecular
products can be made by biotechnology using available feedstocks●How new systems and …

New views on PII signaling: from nitrogen sensing to global metabolic control

K Forchhammer, KA Selim, LF Huergo - Trends in Microbiology, 2022 - cell.com
PII proteins are multitasking information-processing proteins occurring in bacteria, archaea,
and plastids, decoding the metabolic state of the cells and providing this information to …

The emergence of 2-oxoglutarate as a master regulator metabolite

LF Huergo, R Dixon - Microbiology and Molecular Biology …, 2015 - journals.asm.org
The metabolite 2-oxoglutarate (also known as α-ketoglutarate, 2-ketoglutaric acid, or
oxoglutaric acid) lies at the intersection between the carbon and nitrogen metabolic …

A jack of all trades: the multiple roles of the unique essential second messenger cyclic di‐AMP

FM Commichau, A Dickmanns, J Gundlach… - Molecular …, 2015 - Wiley Online Library
Second messengers are key components of many signal transduction pathways. In addition
to cyclic AMP, pp G pp and cyclic di‐GMP, many bacteria use also cyclic di‐AMP as a …

Enhancement of docosahexaenoic acid production by overexpression of ATP-citrate lyase and acetyl-CoA carboxylase in Schizochytrium sp.

X Han, Z Zhao, Y Wen, Z Chen - Biotechnology for Biofuels, 2020 - Springer
Background Docosahexaenoic acid (DHA) is an important omega-3 long-chain
polyunsaturated fatty acid that has a variety of physiological functions for infant development …

Regulation and structure of the heteromeric acetyl-CoA carboxylase

MJ Salie, JJ Thelen - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2016 - Elsevier
The enzyme acetyl-CoA carboxylase (ACCase) catalyzes the committed step of the de novo
fatty acid biosynthesis (FAS) pathway by converting acetyl-CoA to malonyl-CoA. Two forms …

Sensory properties of the PII signalling protein family

K Forchhammer, J Lüddecke - The FEBS journal, 2016 - Wiley Online Library
PII signalling proteins constitute one of the largest families of signalling proteins in nature.
An even larger superfamily of trimeric sensory proteins with the same architectural principle …