The native chemical ligation reaction (NCL) involves reacting a C-terminal peptide thioester
with an N-terminal cysteinyl peptide to produce a native peptide bond between the two …

The amide functional group plays a key role in the composition of biomolecules, including
many clinically approved drugs. Bioisosterism is widely employed in the rational …

Hexagonal mesoporous silica (HMS) supported copper oxide nanoparticles were prepared
by a one-pot sol–gel synthesis, and their physicochemical properties were determined by …

Homogeneous catalysis of organic transformations by metal complexes has been mostly
based on complexes of noble metals. In recent years, tremendous progress has been made …

Bioorthogonal reactions have found widespread use in applications ranging from glycan
engineering to in vivo imaging. Researchers have devised numerous reactions that can be …

Conversion into high-value-added organic nitrogen compounds through electrochemical CN
coupling reactions under ambient conditions is regarded as a sustainable development …

In this contribution, we provide a comprehensive overview of acyclic twisted amides,
covering the literature since 1993 (the year of the first recognized report on acyclic twisted …

The development of new green methodologies and their broader adoption for promoting
sustainable development in chemistry laboratories and industry play a significant role in …

Conspectus Transition-metal-catalyzed cross-coupling reactions represent a most powerful
tool for the rapid construction of C–C and C–X bonds available to synthetic chemists …

This review describes the practical aspects involved in the implementation of large-scale
amidations in process chemistry. Coupling reagent, base, additive, and solvent selections …