Modelling microbial infection to address global health challenges

MC Fitzpatrick, CT Bauch, JP Townsend… - Nature microbiology, 2019 - nature.com
The continued growth of the world's population and increased interconnectivity heighten the
risk that infectious diseases pose for human health worldwide. Epidemiological modelling is …

Calibration of individual-based models to epidemiological data: A systematic review

CM Hazelbag, J Dushoff, EM Dominic… - PLoS computational …, 2020 - journals.plos.org
Individual-based models (IBMs) informing public health policy should be calibrated to data
and provide estimates of uncertainty. Two main components of model-calibration methods …

Individual and network factors associated with racial disparities in HIV among young men who have sex with men: results from the RADAR cohort study

B Mustanski, E Morgan, R D'Aquila… - JAIDS Journal of …, 2019 - journals.lww.com
Background: Individual sexual risk behaviors have failed to explain the observed racial
disparity in HIV acquisition. To increase understanding of potential drivers in disparities, we …

[HTML][HTML] Egocentric sexual networks of men who have sex with men in the United States: results from the ARTnet study

KM Weiss, SM Goodreau, M Morris, P Prasad… - Epidemics, 2020 - Elsevier
In this paper, we present an overview and descriptive results from one of the first egocentric
network studies of men who have sex with men (MSM) from across the United States: the …

Inference of transmission network structure from HIV phylogenetic trees

F Giardina, EO Romero-Severson, J Albert… - PLoS computational …, 2017 - journals.plos.org
Phylogenetic inference is an attractive means to reconstruct transmission histories and
epidemics. However, there is not a perfect correspondence between transmission history …

Evolutionary dynamics and complicated genetic transmission network patterns of HIV-1 CRF01_AE among MSM in Shanghai, China

X Li, Y Xue, Y Lin, J Gai, L Zhang, H Cheng, Z Ning… - Scientific reports, 2016 - nature.com
To explore the evolutionary dynamics and molecular transmission patterns of HIV-1
CRF01_AE in depth among men who have sex with men (MSM) in Shanghai, we …

Impact of early initiation versus national standard of care of antiretroviral therapy in Swaziland's public sector health system: study protocol for a stepped-wedge …

FJ Walsh, T Bärnighausen, W Delva, Y Fleming… - Trials, 2017 - Springer
Background There is robust clinical evidence to support offering early access to antiretroviral
treatment (ART) to all HIV-positive individuals, irrespective of disease stage, to both improve …

Using molecular transmission networks to understand the epidemic characteristics of HIV-1 CRF08_BC across China

K Li, M Liu, H Chen, J Li, Y Liang, Y Feng… - Emerging Microbes & …, 2021 - Taylor & Francis
ABSTRACT HIV-1 CRF08_BC has become a major epidemic in heterosexuals and
intravenous drug users (IDUs) in southern China. In order to evaluate the trends of its …

Leveraging phylogenetics to understand HIV transmission and partner notification networks

DK Pasquale, IA Doherty, LA Sampson… - JAIDS Journal of …, 2018 - journals.lww.com
Background: Partner notification is an important component of public health test and treat
interventions. To enhance this essential function, we assessed the potential for molecular …

HIV-1 molecular transmission network among sexually transmitted populations in Liaoning Province, China

N Ma, X Chen, Y Zhao, X Kang, S Pan, W Yao - Medicine, 2021 - journals.lww.com
Methods: A study of HIV-infected persons who were sexually transmitted in Liaoning
Province from 2003 to 2019. HIV-1 RNA was extracted, amplified and sequenced, and a …