Biological membranes and membrane proteins, responsible for numerous exciting
biological processes, present one of the paramount challenges in biophysics today …

A group of interesting molecules called defensins exhibit multiple functions but have been
primarily recognized to possess a broad spectrum of antimicrobial activities. Studies have …

LL-37 is an amphipathic, α-helical, antimicrobial peptide. 15N chemical shift and 15N
dipolar− shift spectroscopy of site-specifically labeled LL-37 in oriented lipid bilayers …

In this work, we present the first characterization of the cell lysing mechanism of MSI-78, an
antimicrobial peptide. MSI-78 is an amphipathic α-helical peptide designed by Genaera …

Immunomodulatory Siglecs are controlled by their glycoprotein and glycolipid ligands.
Siglec-glycolipid interactions are often studied outside the context of a lipid bilayer, missing …

The misfolding, amyloid aggregation, and fibril formation of intrinsically disordered
proteins/peptides (or amyloid proteins) have been shown to cause a number of disorders …

The 18.5 kDa isoform of myelin basic protein (MBP) is a major component of the myelin
sheath in the central nervous system of higher vertebrates, and a member of a larger family …

The chemical shift of a nucleus, i, in a molecule arises from the nuclear shielding effect of an
applied magnetic field, caused by an induced magnetic field resulting from circulation of …

The mechanism of membrane interaction of two amphipathic antimicrobial peptides, MSI-78
and MSI-594, derived from magainin-2 and melittin, is presented. Both the peptides show …

Atomic force microscopy (AFM) is employed to observe the effect of poly
(amidoamine)(PAMAM) dendrimers on 1, 2-dimyristoyl-sn-glycero-3-phosphocholine …